Results 11 to 20 of about 43,652 (215)

Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017

Frontiers in Medicine, 2023
Background/aimsUveal melanoma is the most common type of non-cutaneous melanoma and the most common ocular malignancy in the adult population, especially affecting Caucasians (98% of cases).
Santina Conte, François Lagacé, Feras M. Ghazawi, Leila Cattelan, Siddharth Nath, Jobanpreet Dhillon, Hacene Nedjar, Elham Rahme, Denis Sasseville, Miguel N. Burnier, Ivan V. Litvinov, Ivan V. Litvinov   +11 more
doaj   +1 more source

A comparative transcriptomic analysis of uveal melanoma and normal uveal melanocyte. [PDF]

PLoS ONE, 2011
BACKGROUND: Uveal melanoma is the most common primary intraocular tumor in adults in western countries. It is associated with very severe visual morbidity and may lead to distant metastases even after successful treatment of the primary tumor.
Jianhong An, Haolei Wan, Xiangtian Zhou, Dan-Ning Hu, Ledan Wang, Lili Hao, Dongsheng Yan, Fanjun Shi, Zhonglou Zhou, Jiao Wang, Songnian Hu, Jun Yu, Jia Qu   +12 more
doaj   +1 more source

Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. [PDF]

, 2017
Patients with metastatic uveal melanoma usually die within 1 year of diagnosis, emphasizing an urgent need to develop new treatment strategies. The liver is the most common site of metastasis.
Aplin, Andrew E., Cheng, Hanyin, Chua, Vivian, Davies, Michael A., Kageyama, Ken, Liao, Connie, Purwin, Timothy J., Sato, Takami, Terai, Mizue   +8 more
core   +2 more sources

The diagnosis of metastatic uveal melanoma. What has changed during 10 years?

Alʹmanah Kliničeskoj Mediciny, 2020
Uveal melanoma is the most common intraocular malignancy. Despite significant progress in the treatment of the primary tumor, uveal melanoma continues to be the most aggressive tumor due to its high potential for hematogenous metastatic spread.
E. E. Grishina, E. A. Stepanova, A. M. Bogatyrev   +2 more
doaj   +1 more source

The prognostic implication of latitude in uveal melanoma: a nationwide observational cohort study of all patients born in Sweden between 1947 and 1989

Discover Oncology, 2022
Background The incidence of uveal melanoma increases with latitude. In this study, we examine the importance of latitude for uveal melanoma prognosis. Methods All uveal melanoma patients born in Sweden between 1947 and 1990 were included (n = 745).
Gustav Stålhammar, Pete A. Williams, Tomas Landelius   +2 more
doaj   +1 more source

Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]

, 2008
<p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
Aziz, S., Kacperek, A., Kemp, E., McConnachie, A., Taylor, A.   +4 more
core   +3 more sources

Osteopontin and `Melanoma Inhibitory Activity': Comparison of Two Serological Tumor Markers in Metastatic Uveal Melanoma Patients [PDF]

, 2009
Background: Evaluation of the protein osteopontin (OPN) as a potential new marker in comparison to melanoma inhibitory activity (MIA) for screening and detection of metastatic uveal melanoma. Methods: Plasma levels of 32 patients with uveal melanoma were
Haritoglou, Christos, Haritoglou, Ingrid, Hein, Ruediger, Maier, Tanja, Schaller, Ulrich Christoph, Wolf, Armin   +5 more
core   +1 more source

MiR-144 Inhibits Uveal Melanoma Cell Proliferation and Invasion by Regulating c-Met Expression. [PDF]

PLoS ONE, 2015
MicroRNAs (miRNAs) are a group endogenous small non-coding RNAs that inhibit protein translation through binding to specific target mRNAs. Recent studies have demonstrated that miRNAs are implicated in the development of cancer.
Lei Sun, Guangqing Bian, ZhaoJun Meng, Guangfu Dang, DeJing Shi, Shuyong Mi   +5 more
doaj   +1 more source

Epidemiology of uveal melanomas in Moscow

Alʹmanah Kliničeskoj Mediciny, 2017
Rationale: Melanoma of the uveal tract of the eye is among the most prevalent malignant intraocular tumors.Aim: To identify epidemiological characteristics of uveal melanoma in Moscow.Materials and methods: We performed a retrospective analysis of out ...
E. E. Grishina, M. Yu. Lerner, E. G. Gemdzhian   +2 more
doaj   +1 more source

Features of effector lymphocyte subsets in patients with uveal melanoma in recurrent and chronic herpesvirus infection

Инфекция и иммунитет, 2022
The aim of the study is to conduct a comparative analysis of percentages for peripheral blood effector lymphocyte subsets in patients with uveal melanoma manifested by recurrent and chronic herpesvirus infection.
N. V. Balatskaya, S. V. Saakyan, E. B. Myakoshina, I. G. Kulikova, G. I. Krichevskaya   +4 more
doaj   +1 more source