Local treatment failure after globe-conserving therapy for choroidal melanoma. [PDF]
, 2013 Local treatment failure after globe-conserving therapy for choroidal melanoma is a surgical complication with significant morbidity to the vision and eye. Few reports in the literature have addressed this complication exclusively.
Chang, Melinda Y, McCannel, Tara A
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Scientific and clinical implications of genetic and cellular heterogeneity in uveal melanoma
Molecular Biomedicine, 2021 Here, we discuss the presence and roles of heterogeneity in the development of uveal melanoma. Both genetic and cellular heterogeneity are considered, as their presence became undeniable due to single cell approaches that have recently been used in uveal
Mark J. de Lange +2 more
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Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma
Medicina, 2023 Both cutaneous melanoma (CM) and uveal melanoma (UM) represent important causes of morbidity and mortality. In this review, we evaluate the available knowledge on the differences and similarities between cutaneous melanoma and uveal melanoma, focusing on
Daciana Elena Brănișteanu +10 more
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Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
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Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma [PDF]
, 2017 Uveal melanoma is the most common intraocular malignancy in adults. The lack of an effective treatment results in a median survival time less than one year for patients with metastatic disease.
De Paepe, Boel +7 more
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The reporting of uveal melanoma cases to the cancer registry in North Carolina
Frontiers in Oncology, 2022 ObjectiveTo ascertain the completeness of reporting of uveal melanoma cases in North Carolina to the state’s cancer registry.MethodsThis was a retrospective chart review performed at a single institution analyzing the completeness of information reported
Kathleen G. Gordon +3 more
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Insights into Imaging, 2021 Uveal melanoma is a malignant neoplasm that derives from pigmented melanocytes of the uvea and involves, in order of decreasing prevalence, the choroid, ciliary body and iris.
Pietro Valerio Foti +16 more
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Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment. [PDF]
, 2017 CXCR1 and CXCR2 chemokine receptors and their ligands (CXCL1/2/3/7/8) play an important role in tumor progression. Tested to date CXCR1/2 antagonists and chemokine-targeted antibodies were reported to affect malignant cells in vitro and in animal models.
Alexeev, Vitali +10 more
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Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma. [PDF]
, 2015 Uveal melanoma patients with metastatic disease usually die within one year, emphasizing an urgent need to develop new treatment strategies for this cancer.
Aplin, Andrew E. +6 more
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Immunohistochemical Expression of ABCB5 as a Potential Prognostic Factor in Uveal Melanoma
Applied Sciences, 2019 Uveal melanoma represents the most common primary intraocular malignancy in adults; it may arise in any part of the uveal tract, with choroid and ciliary bodies being the most frequent sites of disease.
Giuseppe Broggi +7 more
doaj +1 more source