Results 31 to 40 of about 43,652 (215)
Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
American Journal of Ophthalmology Case Reports, 2021 Purpose: To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments. Observations: The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-
Yewlin E. Chee +8 more
doaj +1 more source
The clinical and histopathological features of patients with both uveal and cutaneous melanoma
The Pan-American Journal of Ophthalmology, 2020 Introduction: It is unusual to have uveal and cutaneous melanoma in the same patient. It is challenging to differentiate between primary uveal melanoma (UM) and melanoma metastatic to the uvea.
Anelise Savaris Dias +7 more
doaj +1 more source
BAP1 methylation: a prognostic marker of uveal melanoma metastasis
npj Precision Oncology, 2021 Uveal melanoma, the most common intraocular primary cancer in adults, is characterized by striking variability in metastatic tendencies. BAP1 deletion in the primary tumor is associated with uveal melanoma metastasis, but it cannot always be resolved by ...
Mathieu F. Bakhoum +3 more
doaj +1 more source
Успехи молекулярной онкологии, 2022 Introduction. Uveal melanoma ability to metastasize depends on a few prognostic factors. The genetic ones are considered to be the most significant. The role of disorders of the short arm of chromosome 8 (8p), as well as a combination of changes in 8p ...
V. A. Yarovaya +4 more
doaj +1 more source
Necrotic uveal melanoma presenting as orbital cellulitis with intraocular hemorrhage: A case report
American Journal of Ophthalmology Case Reports, 2019 Purpose: To report a case of necrotic uveal melanoma presenting as orbital cellulitis with an intraocular hemorrhage. Observations: A 61 year-old non-verbal male presented with a two-week history of right eyelid swelling and erythema unresponsive to ...
Alexa L. Li +4 more
doaj +1 more source
Uveal melanoma incidentally diagnosed with neuroimaging, a case series of 3 patients
Radiology Case Reports, 2022 Uveal melanoma is the most common primary intraocular malignancy and can occur in the choroid, the ciliary body, or the iris. It is most often diagnosed based on clinical examination by an ophthalmologist. Nearly all patients present with visual symptoms.
Mai Tsukikawa, MD +4 more
doaj +1 more source
Immunological backbone of uveal melanoma: is there a rationale for immunotherapy? [PDF]
, 2019 No standard treatment has been established for metastatic uveal melanoma (mUM). Immunotherapy is commonly used for this disease even though UM has not been included in phase III clinical trials with checkpoint inhibitors.
Alessandra Cassano +24 more
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Uveal melanoma: Estimating prognosis
Indian Journal of Ophthalmology, 2015 Uveal melanoma is the most common primary malignant tumor of the eye in adults, predominantly found in Caucasians. Local tumor control of uveal melanoma is excellent, yet this malignancy is associated with relatively high mortality secondary to ...
Swathi Kaliki +2 more
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Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression. [PDF]
PLoS ONE, 2012 Uveal melanoma is an aggressive cancer that metastasizes to the liver in about half of the patients, with a high lethality rate. Identification of patients at high risk of metastases may provide indication for a frequent follow-up for early detection of ...
Rosaria Gangemi +18 more
doaj +1 more source
Expression of Tryptophan 2,3-Dioxygenase in Metastatic Uveal Melanoma [PDF]
, 2020 Uveal melanoma (UM) is the most common primary eye malignancy in adults and up to 50% of patients subsequently develop systemic metastasis. Metastatic uveal melanoma (MUM) is highly resistant to immunotherapy.
Bhushan, Alok +8 more
core +1 more source