Characterization of Luteinizing hormone-releasing hormone (LH-RH-I) receptor type I as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines [PDF]
K
Dobos, Nikoletta +8 more
core +1 more source
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. [PDF]
BRAF and NRAS are common targets for somatic mutations in benign and malignant neoplasms that arise from melanocytes situated in epithelial structures, and lead to constitutive activation of the mitogen-activated protein (MAP) kinase pathway.
Barsh, Gregory S +8 more
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Cystoid macular edema as the initial manifestation of choroidal melanoma
Uveal melanomas are a common clinical entity that initially present in a variety of ways. Cystoid macular edema is caused by many conditions, but it is rarely associated with uveal melanoma.
Robert B Garoon +3 more
doaj +1 more source
Jefferson Digital Commons quarterly report: October-December 2019 [PDF]
This quarterly report includes: Articles Dean\u27s Research Development Lunch Conference Dissertations Educational Materials From the Archives Grand Rounds and Lectures Journals and Newsletters Population Health Presentation Materials Posters Reports ...
Copeland, LIBT, James +2 more
core +2 more sources
Genetic Prognostic Factors and Follow-up in Uveal Melanoma [PDF]
An important part of oncological research is to identify prognostic factors and predict which patients are at risk for (early) metastasis. This thesis aims to describe the known genetic alterations in uveal melanoma and define new chromosomal regions and
Bosch, T. (Thomas) van den
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Testing patients with uveal melanoma for herpesvirus infections
Results of comprehensive ELISA tests of blood serum for the presence of IgM-, IgA-, and IgG-antibodies to herpes simplex virus types 1 and 2, cytomegalovirus, Epstein-Barr virus, human herpesvirus 6, human herpes virus 8 type, Chlamydia trachomatis in 38
S. V. Saakyan +7 more
doaj +1 more source
Cytogenetic analysis of uveal melanomas: a long-term experience [PDF]
Background/aim: Cytogenetic profile of posterior uveal melanoma (mainly monosomy 3) is actually considered the most specific prognostic factor for uveal melanoma patients.
Parrozzani, Raffaele
core +1 more source
The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J +3 more
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Clinical and genetic characteristics of BAP1-mutated non-uveal and uveal melanoma
BackgroundScreening for gene mutations has become routine clinical practice across numerous tumor entities, including melanoma. BAP1 gene mutations have been identified in various tumor types and acknowledged as a critical event in metastatic uveal ...
Johanna Matull +25 more
doaj +1 more source
Cellular radiosensitivity of primary and metastatic human uveal melanoma cell lines [PDF]
PURPOSE: To investigate the radiosensitivity of uveal melanoma cell lines by a clonogenic survival assay, to improve the efficiency of the radiation regimen. METHODS: Four primary and four metastatic human uveal melanoma cell lines were
Aardweg, G.J.M.J. (Gerard) van den +4 more
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