Results 1 to 10 of about 356,274 (192)

Canine and feline uveal melanocytic tumours: Histologic and immunohistochemical characteristics of 32 cases

open access: yesVeterinary Medicine and Science, 2022
Objective Gross, histopathological, and immunohistochemical characteristics of uveal melanocytic neoplasms in dogs and cats were investigated. Samples Thirty‐two enucleated globes with uveal melanocytic neoplasms, 27 from dogs and 5 from cats, were ...
Matheus Vilardo Lóes Moreira   +7 more
doaj   +2 more sources

Second Primary Neoplasms in Patients With Uveal Melanoma: A SEER Database Analysis [PDF]

open access: yesAmerican Journal of Ophthalmology, 2016
To determine the risk of second primary neoplasms (SPNs) in subjects previously diagnosed with uveal melanoma (UM), including an analysis on whether radiotherapy is a risk factor to develop these SPNs.Retrospective cohort study.Using the Surveillance, Epidemiology, and End Results (SEER) 9 database, we identified patients diagnosed with UM as their ...
Laíns, I   +6 more
openaire   +4 more sources

SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas [PDF]

open access: yesActa Neuropathologica Communications, 2016
Like uveal melanomas, primary leptomeningeal melanocytic neoplasms (LMNs) frequently carry GNAQ and GNA11 mutations. However, it is currently unknown whether these LMNs harbor mutations in BAP1, SF3B1 and/or EIF1AX like uveal melanomas as well. In this study, we used Sanger sequencing for the detection of mutations in SF3B1 (hotspots in exon 14 and 15)
Küsters-Vandeveld, Heidi VN   +9 more
openaire   +9 more sources

Presumed Melanoma of Unknown Primary Origin Metastatic to the Choroid Mimics Primary Uveal Melanoma

open access: yesCase Reports in Ophthalmology, 2021
We describe the case of a 69-year-old woman who presented with a decline in vision in the left eye and was found to have a choroidal lesion with clinical and echographic features concerning for primary uveal melanoma. Systemic imaging identified numerous
John M. Rieth   +4 more
doaj   +2 more sources

Isolated chemohyperthermal perfusion of the liver with melphalan in the treatment of unresectable liver metastases with uveal melanoma

open access: yesИсследования и практика в медицине, 2021
Uveal melanoma belongs to rare malignant neoplasms, and the biological peculiarity of this tumor determines the high rate of distant metastasis, which reaches 60 %.
A. D. Kaprin   +7 more
doaj   +2 more sources

Epidemiology of neoplasms of the eye and adnexa in Orenburg region

open access: yesРоссийский офтальмологический журнал, 2022
Purpose. To analyze the incidence of neoplasms of the eye and its appendages among residents of the Orenburg region, and determine its structure and dynamics within a 5-year period (2013 to 2017).Material and methods.
A. E. Aprelev   +3 more
doaj   +2 more sources

SOX10 Expression as Well as BRAF and GNAQ/11 Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas

open access: yesInvestigative Opthalmology & Visual Science, 2017
Adenocarcinomas or adenomas derived from pigmented ciliary epithelium (APCE) are exceptionally rare ocular tumors. These tumors have pigmented and epithelioid features, and some APCEs are negative for keratin markers and positive for melanocytic markers. It is especially difficult to distinguish APCEs from uveal melanoma (UM).
Taisuke, Mori   +7 more
openaire   +3 more sources

Expression of cyclooxygenase-2 in canine uveal melanocytic neoplasms

open access: yesAmerican Journal of Veterinary Research, 2009
Abstract Objective—To determine whether cyclooxygenase-2 (COX-2) is expressed in benign or malignant canine uveal melanocytic neoplasms and whether expression correlates with malignancy. Sample Population—Tissue sections from 71 globes; 57 with benign (n = 15), malignant (34), or mixed (8) uveal melanocytic neoplasms; 10 with nonneoplastic disease; and
Danielle, Paglia   +3 more
openaire   +3 more sources

Systemic anti-CD20 (rituximab) as primary treatment for symptomatic primary uveal lymphoma

open access: yesAmerican Journal of Ophthalmology Case Reports, 2019
Purpose: Uveal lymphomas are indolent, frequently choroid-involving neoplasms that are mainly CD20-positive B-cell extranodal marginal zone lymphoma. Irreversible visual loss may occur from retinal detachment and/or glaucoma among untreated symptomatic ...
Honeylen Maryl Tiu Teo   +3 more
doaj   +2 more sources

Immunoexpression of Macroh2a in Uveal Melanoma

open access: yesApplied Sciences, 2019
MacroH2A is a histone variant whose expression has been studied in several neoplasms, including cutaneous melanomas (CMs). In the literature, it has been demonstrated that macroH2A.1 levels gradually decrease during CM progression, and a high expression ...
Lucia Salvatorelli   +9 more
doaj   +2 more sources

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