Results 121 to 130 of about 882 (153)
In vivo pharmacokinetic analysis of meropenem/vaborbactam during continuous venovenous haemodialysis
Christopher Miller, Bryan T Mogle
exaly +3 more sources
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Meropenem/Vaborbactam, the First Carbapenem/β-Lactamase Inhibitor Combination
Annals of Pharmacotherapy, 2018Objective: To review the pharmacology, spectrum of activity, pharmacokinetics, pharmacodynamics, safety, efficacy, administration, and considerations for clinical use of meropenem/vaborbactam (M/V). Data Sources: A literature search using PubMed and clinicaltrials.gov (June 2013 to December 2017) was conducted using the search terms meropenem ...
Jonathan C, Cho +3 more
openaire +2 more sources
Pharmacokinetic evaluation of meropenem and vaborbactam for the treatment of urinary tract infection
Expert Opinion on Drug Metabolism & Toxicology, 2018Meropenem/vaborbactam (M/V) represents the first carbapenem and β-lactamase inhibitor combination approved for treatment of complicated urinary tract infections (cUTIs), including pyelonephritis. Vaborbactam is a novel boronic acid, β-lactamase inhibitor with a high affinity for serine β-lactamases, including Klebsiella pneumoniae carbapenemase (KPC ...
Rodrigo M, Burgos +3 more
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A Brief Review of a New Antibiotic: Meropenem-vaborbactam
The Senior Care Pharmacist, 2019Meropenem-vaborbactam is a newly approved antibiotic for complex urinary tract infections and to treat carbapenem-resistant Enterobacteriaceae infections. Its advantage over meropenem is the betalactamase inhibitor which slows bacterial resistance. This medication has been studied in numerous countries and has relatively few side effects.
openaire +2 more sources
Meropenem / Meropenem-vaborbactam
2017Meropenem is a broad-spectrum parenteral carbapenem with antimicrobial activity against a wide range of Gramnegative and Gram-positive bacteria, including anaerobes. As a consequence of emerging multidrug resistance, especially in Gram-negative organisms, the clinical reliance on meropenem and other carbapenems increased after their introduction ...
Peleg, A. Y., Harris, P.
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Meropenem/Vaborbactam in Pediatrics: 2 Cases of CRE Intraabdominal Infection
The Journal of Pediatric Pharmacology and TherapeuticsMeropenem/vaborbactam is a combination antibiotic with a carbapenem and a carbapenemase inhibitor typically reserved for extensively drug-resistant bacterial infections, such as carbapenem-resistant Enterobacterales (CRE). Meropenem/vaborbactam is approved by the United States Food and Drug Administration for use in adults for complicated urinary tract
Ugene, Sano +3 more
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