Results 61 to 70 of about 9,622 (181)
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot +3 more
wiley +1 more source
A Large Vaccine‐Derived Poliovirus Outbreak on Madura Island—Indonesia, 2005 [PDF]
Between June and October 2005, 45 laboratory-confirmed type 1 vaccine-derived poliovirus (VDPV) cases were identified on Madura Island in Indonesia. Genetic sequencing data on VDPV isolates were consistent with replication and circulation for up to approximately 2 years.
Concepción F, Estívariz +10 more
openaire +2 more sources
Compost teas derived from bell pepper and citrus waste are rich in bioactive phenolics and lignin derivatives, showing strong antibacterial activity against gram‐positive bacteria and potent antiviral effects against HSV‐1 and RSV. These findings highlight their potential as sustainable, circular bioresources for biomedical applications.
Maria Vittoria Verrillo +7 more
wiley +1 more source
This is the first report of persistent oropharyngeal mucosal infection with type 2 poliovirus (iVDPV2) in a primary immune deficient patient (PID) after wild type 2 poliovirus eradication. The iVDPV2 also established persistence in the gut.
Merav Weil +11 more
doaj +1 more source
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Detection of vaccine-derived poliovirus type-3 in sewage of Kathmandu Valley, Nepal
Enteroviruses include polioviruses, which are classified into three types: type 1, type 2, and type 3. The oral polio vaccine (OPV), which contains attenuated strains of these three types, has been pivotal in reducing polio incidence worldwide.
Rachana Mehta +4 more
doaj +1 more source
Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission.
Since the global withdrawal of Sabin 2 oral poliovirus vaccine (OPV) from routine immunization, the Global Polio Eradication Initiative (GPEI) has reported multiple circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks.
Michael Famulare +12 more
doaj +1 more source
Breast Cancer: Molecular Pathogenesis, Targeted Therapy, Screening, and Prevention
The review manuscript examines the molecular pathogenesis, screening, prevention advances, and evolving targeted therapies in breast cancer. It highlights the integration of AI and multiomics for precision prevention and personalized treatment, pointing toward future directions in equitable cancer care.
Huijun Lei +7 more
wiley +1 more source
Long-Term Excretion of Vaccine-Derived Poliovirus by a Healthy Child [PDF]
ABSTRACT A child was found to be excreting type 1 vaccine-derived poliovirus (VDPV) with a 1.1% sequence drift from Sabin type 1 vaccine strain in the VP1 coding region 6 months after he was immunized with oral live polio vaccine. Seventeen type 1 poliovirus isolates were recovered from stools taken from this child during the following 4 ...
Javier, Martín +9 more
openaire +2 more sources
Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley +1 more source

