Results 1 to 10 of about 495,603 (297)

A Novel High-Potency Tetanus Vaccine

open access: yesmBio, 2020
Chemically inactivated tetanus toxoid (CITT) is clinically effective and widely used. However, CITT is a crude nonmalleable vaccine that contains hundreds of Clostridium tetani proteins, and the active component is present in variable and sometimes minor
Amanda Przedpelski   +4 more
doaj   +3 more sources

Analysing the Potency of a Seasonal Influenza Vaccine Using Reference Antisera from Heterologous Strains

open access: yesVaccines
The potency of inactivated seasonal influenza vaccine is harmonised by establishing the haemagglutinin (HA) content using the compendial single radial diffusion (SRD) method.
Christine Wadey, Steven Rockman
doaj   +3 more sources

Development of an ELISA-Based Potency Assay for Inactivated Influenza Vaccines Using Cross-Reactive Nanobodies

open access: yesVaccines, 2022
Inactivated vaccines are the main influenza vaccines used today; these are usually presented as split (detergent-disrupted) or subunit vaccines, while whole-virus-inactivated influenza vaccines are rare. The single radial immune diffusion (SRD) assay has
Chung Y. Cheung   +8 more
doaj   +1 more source

EFFECT OF STORAGE TEMPRATURE ON THE KEEPING QUALITY OF OIL ADJUVANTED FMD VACCINE [PDF]

open access: yesVeterinary Medical Journal - Giza, 2006
In this study, inactivated oil FMD vaccine adjuvanted with ISA 206 was prepared. Guinea pig potency testing was applied to determine the ultimate shelf life of oil adjuvanted FMD vaccine at different conditions of storage temperatures.
M RABIE, H FAWZY, A AGGOUR
doaj   +1 more source

Correlation Study of the Most Important Environmental Influencing Factors on the Razi MMR Vaccine [PDF]

open access: yesArchives of Razi Institute, 2021
Measles, mumps, and rubella (MMR) are among the most important viral infectious diseases in Iran and neighboring countries. After using a trivalent vaccine for these three diseases for a long time, in recent years, these diseases have been significantly ...
S Soleimani, S Rashid
doaj   +1 more source

Assessment of in vitro potency of inactivated Newcastle disease oil adjuvanted vaccines using hemagglutination test and blocking ELISA [PDF]

open access: yesVeterinary World, 2018
Aim: The present study was aimed to establish a protocol for the evaluation of the in vitro potency of commercial inactivated Newcastle disease virus (NDV) oil-adjuvanted vaccines using hemagglutination test (HA) and blocking ELISA (B-ELISA) based on ...
Saleh E. Aly   +4 more
doaj   +1 more source

Development of functionally relevant potency assays for monovalent and multivalent vaccines delivered by evolving technologies

open access: yesnpj Vaccines, 2022
A potency or potency-indicating assay is a regulatory requirement for the release of every lot of a vaccine. Potency is a critical quality attribute that is also monitored as a stability indicator of a vaccine product.
Gautam Sanyal
doaj   +1 more source

RAPID EVALUATION OF LIVE ATTENUATED AND INACTIVATED RIFT VALLEY FEVER VACCINES IN-VITRO [PDF]

open access: yesAssiut Veterinary Medical Journal, 1997
Indirect immunofluorescence assay (IFA) was used for detection, identification and titration live attenuated RVF (7.5 log10 TCID 50 / ml) as well as inactivated alum gel RVF.
M.S. WASSEL   +3 more
doaj   +1 more source

Effect of freezing on recombinant hepatitis E vaccine

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Studies have revealed that vaccines are more often exposed to sub-zero temperatures during cold chain transportation than what was previously known. Such exposure might be detrimental to the potency of temperature-sensitive vaccines.
Kelei Li   +10 more
doaj   +1 more source

Short communication: Feasibility of dengue vaccine to infect different human cell lines: An alternative potency test using HEK293T cells.

open access: yesPLoS ONE, 2022
Dengue is caused by an arbovirus that belongs to the Flaviviridae family and there are four distinct, but close related, circulating serotypes. Dengue disease is of great importance for global public health, with vaccination being its main prophylactic ...
Renata Faria de Carvalho   +4 more
doaj   +1 more source

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