Results 121 to 130 of about 495,603 (297)

Safety and Potential Test Profile of Inactivated Coryza Vaccine in SPF Chickens

Journal of Applied Veterinary Science and Technology
Background: Infectious coryza, caused by Avibacterium paragallinarum, is an acute and highly contagious respiratory disease in chickens that results in high morbidity, growth retardation, and decreased egg production, leading to economic losses in ...
Shilva Givanny Saiful, Mohandas Indradji, Diana Indrasanti, Ernes Andesfha   +3 more
doaj   +1 more source

Evaluating the safety of influenza vaccine using a claims-based health system

, 2017
Introduction: As part of the Centers for Disease Control and Prevention's monitoring and evaluation activities for influenza vaccines, we examined relationships between influenza vaccination and selected outcomes in the 2009-2010 and 2010-2011 influenza ...
McCarthy, Natalie L.;Gee, Julianne;Lin, Nancy D.;Thyagarajan, Veena;Pan, Yi;Su, Sue;Turnbull, Bruce;Chan, K. Arnold;Weintraub, Eric, 陳建煒   +1 more
core   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency. [PDF]

J Control Release, 2022
Anderluzzi G, Lou G, Woods S, Schmidt ST, Gallorini S, Brazzoli M, Johnson R, Roberts CW, O'Hagan DT, Baudner BC, Perrie Y.   +10 more
europepmc   +1 more source

Updated recommendations of the International dengue Initiative expert group for CYD-TDV vaccine implementation in Latin America

, 2019
Dengue disease represents a large and growing global threat to public health, causing a significant burden to health systems of endemic countries. For countries considering vaccination as part of their Integrated Management Strategy for Prevention and ...
Giambernardino, H. I.G., Castellanos-Martinez, J. M., Delrieu, Isabelle, Avila-Aguero, Maria L., Torres, Jaime, Torres, C. N, Falleiros-Arlant, Luiza Helena, Brea, J., Gessner, Bradford D., Mascareñas, Abiel   +9 more
core   +1 more source

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

Advanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang, Min Li, Zhiying Yao, Yu Hu, Zhili Wang, Wendi Shi, Bingbing Sun   +6 more
wiley   +1 more source

Potency Testing for NTD Vaccines: Determining Relative Potency for the Na-GST-1 Human Hookworm Vaccine [PDF]

, 2011
Over the next decade, a new generation of vaccines will target the neglected tropical diseases (NTDs) . The goal of most NTD vaccines will be to reduce the morbidity and decrease the chronic debilitating nature of these often-forgotten infections ...
Bethony, Jeffrey M., Plieskatt, Jordan L., Hotez, Peter J., Jariwala, Amar R, Bottazzi, Maria Elena, Raghavendra, Pavithra, Keegan, Brian   +6 more
core  

Concomitant administration of live attenuated Japanese encephalitis chimeric virus vaccine (JE-CV) and measles, mumps, rubella (MMR) vaccine: Randomized study in toddlers in Taiwan

, 2017
Background: Japanese encephalitis (JE) is the most important cause of viral encephalitis in Asia. ;Methods: In this randomized, open-label, multicenter trial in 550 children aged 12 to 18 months in Taiwan, children received one dose of JE-CV and one dose
Huang, Li-Min;Lin, Tzou-Yien;Chiu, Cheng-Hsun;Chiu, Nan-Chang;Chen, Po-Yen;Yeh, Shu-Jen;Boaz, Mark;Hutagalung, Yanee;Bouckenooghe, Alain;Feroldi, Emmanuel, 黃立民   +1 more
core   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

Establishment of a mouse- and egg-adapted strain for the evaluation of vaccine potency against H3N2 variant influenza virus in mice. [PDF]

J Vet Med Sci, 2021
Bazarragchaa E, Hiono T, Isoda N, Hayashi H, Okamatsu M, Sakoda Y.   +5 more
europepmc   +1 more source