Results 201 to 210 of about 273,408 (290)

Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy

Biotechnology and Bioengineering, EarlyView.
Schematic depicting the workflow for model building and validation using Raman spectroscopy for real‐time monitoring of IVT. ABSTRACT The success of COVID‐19 mRNA vaccines showcased the transformative potential of this adaptable, plug‐and‐play, and rapid response platform.
Julia Puppin Chaves Fulber, Xingge Xu, Hadi El Radi, Kevin Grollier, Amine A. Kamen   +4 more
wiley   +1 more source

Virus-like and Virus Replicon Particles Targeting Multiple B-Cell Antigens Do Not Protect Against African Swine Fever Virus. [PDF]

Vaccines (Basel)
Lotonin K, García-Nicolás O, Kilb N, Krämer S, Chang X, Engeroff P, Mehinagic K, Donzé N, Brito F, Liniger M, Lieknina I, Cernova D, Balta I, González-García G, Rueda P, Zimmer G, Benarafa C, Ruggli N, Roth G, Tars K, Bachmann M, Summerfield A.   +21 more
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Immunogenicity of neoantigens from hepatocellular carcinoma patients treated with a combined radioimmunotherapy. [PDF]

Oncoimmunology
Aparicio B, Silva L, Ruiz M, Llópiz D, Repáraz D, Theunissen P, Tamayo I, Egea J, Igea A, Smerdou C, Peñas M, Perpiñá C, Matilla A, Varela M, Reig M, de la Torre-Alaez M, Argemí J, Sangro B, Hervás-Stubbs S, Sarobe P.   +19 more
europepmc   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Prevention of Porcine Epidemic Diarrhea Virus With Nanotube-Adjuvanted Oral DNA Vaccines. [PDF]

Transbound Emerg Dis
Wu HC, Doan TD, Chang WC, Hsu MK, Wang HY, Liaw J, Chang CJ, Chu CY, Chen NH.   +8 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Harnessing Vaccines in the Treatment of Solid Tumors: Advances, Challenges, and Future Directions. [PDF]

Vaccines (Basel)
Iranzo J, Giordano E, Marsicano RM, Trapani D, Marra A, Belli C, Zagami P, Berton Giachetti PPM, Ferraro E, Minchella I, Crimini E, Curigliano G.   +11 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Therapeutic vaccination for active induction of T cell immunity against cancer, ready for a rich harvest after 40 years. [PDF]

J Immunother Cancer
Melief CJM.
europepmc   +1 more source