Results 191 to 200 of about 123,893 (301)

From bark to bench: innovations in QS-21 adjuvant characterization and manufacturing. [PDF]

Front Immunol
Talukdar P, Winegar PH, Hudson GA, Astolfi MCT, Inman JL, Keasling JD, Mukundan H.   +6 more
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

DNA Vaccines in the Post-mRNA Era: Engineering, Applications, and Emerging Innovations. [PDF]

Int J Mol Sci
Neeli P, Chai D, Roy D, Prajapati S, Bonam SR.   +4 more
europepmc   +1 more source

Stereoselective Ferrier‐Type O‐Glycosylation Enabled by Difluoromethylated Glycal Donors

Advanced Science, EarlyView.
A fluorine‐mediated stereoselective Ferrier‐type glycosylation is reported. Glycals are pre‐decorated with photo‐2‐difluoroalkylation and reacted with diverse acceptors to obtain exclusively α‐selective Ferrier rearrangement products. Abstract The effective construction of structurally homogeneous glycosides is requisite in oligosaccharide assembly and
You Zou, Hengfu Xu, Cang‐Xin Zheng, Weiwei Zhang, Xin‐Shan Ye, De‐Cai Xiong   +5 more
wiley   +1 more source

West Nile Virus: Epidemiology, Surveillance, and Prophylaxis with a Comparative Insight from Italy and Iran. [PDF]

Vaccines (Basel)
Najafi S, Jojani M, Najafi K, Costanzo V, Vicidomini C, Roviello GN.   +5 more
europepmc   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Advancing Peptide-Based Vaccines Against <i>Candida</i>: A Comparative Perspective on Liposomal and Synthetic Formulations. [PDF]

J Fungi (Basel)
Xin H.
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Research progress and applications of reverse genetics systems for infectious bronchitis virus. [PDF]

Poult Sci
Zhao Y.
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source