Results 171 to 180 of about 124,779 (298)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Circular RNA therapeutics: a new class of long-acting RNA medicines for oncology, immunology, and rare diseases. [PDF]

Front Immunol
Ugwu OP, Okon MB, Ogenyi FC, Ugwu JN, Ugwu CN.   +4 more
europepmc   +1 more source

Non-Coding DNA-Derived Mimotopes of Aβ₄₂ as Novel Candidates for Alzheimer's Peptide Vaccine Design. [PDF]

Int J Med Sci
Raj N, R SP, Ammar RB, Rajendran P, Chellappan BV.   +4 more
europepmc   +1 more source

Rational design of next-generation vaccine adjuvants: From molecular mechanisms to hybrid delivery platforms. [PDF]

Hum Vaccin Immunother
Zhao Y, Li J, Chen J, Yang C, Tao J, Zhu R.   +5 more
europepmc   +1 more source

A Bioinspired Approach to Next-Generation Vaccines in Solid Tumors with Engineered Cell Membranes. [PDF]

Research (Wash D C)
Zhang W, Chen M, Huang X.
europepmc   +1 more source

"More" Artificial mRNAs: Beyond the Art of Nature. [PDF]

Adv Sci (Weinh)
Cui Y, Fukui M, Ohno H, Saito H.
europepmc   +1 more source

Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma [PDF]

, 2019
Artyomov, Maxim N., Bender, Diane, Campian, Jian L., Chicoine, Michael R., Dacey, Ralph G., Dunn, Gavin P., Fritsch, Edward F., Gillanders, William E., Huang, Jiayi, Johanns, Tanner M., Kobayashi, Dale K., Liu, Connor J., Mardis, Elaine R., Miller, Christopher A., Perrin, Richard J., Schreiber, Robert D.   +15 more
core   +1 more source

Impact of a community-led intervention on the uptake of childhood vaccines in Liverpool: a protocol for a synthetic control evaluation. [PDF]

BMJ Open
Amin MS, Zhang X, Green MA, Holford D, Hemingway C, Ismail A, Moran J, Doyle V, Taylor C, Taegtmeyer M, Hungerford D.   +10 more
europepmc   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

Beyond the Sequence: Chemical and Topological Design and Innovations in mRNA Therapeutics. [PDF]

Chem Rev
Liu D, Chen H, Pan A, Wang X.
europepmc   +1 more source