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Synthetic Peptide Vaccines for Schistosomiasis
1995Schistosomiasis is a chronic disease that infects an estimated 200 million persons, leading to an estimated 800,000 to 1 million annual deaths. It ranks second only to malaria in terms of morbidity and mortality caused by a parasitic disease. In addition, there is increasing evidence that schistosome infection may have profound effects on growth in ...
D A, Harn +4 more
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Synthetic immunomodulators and synthetic vaccines.
Critical reviews in therapeutic drug carrier systems, 1987Efforts have been made for several years to obtain well-defined, nontoxic adjuvants and antigens which could be used for human vaccination and immunostimulation. Among synthetic adjuvants, MDP represents one of the most studied family of compounds. This molecule is the minimal active structure of whole Mycobacteria and has been shown to be endowed with
C, Leclerc, F R, Vogel
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Synthetic Vaccines — A Dream or Reality
1972A great deal of information has been presented at this conference concerning vaccination and vaccines. This has included modification and improvement of known vaccine preparations or the route of vaccination; the possible use of virus subunits or purified virus proteins in vaccination; and the development of new vaccines with specificities different ...
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Development and application of synthetic peptides as vaccines
Biotechnology Advances, 1989Vaccination against bacterial and viral diseases has been one of the major achievements in medicine and immunology since the beginning of this century. Extensive vaccination programs have been able to control or, in the case of smallpox, virtually wipe out some of the most dangerous infectious diseases e.g.
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The Development of Synthetic Vaccines
Hospital Practice, 1981R A, Lerner +4 more
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Engineering living therapeutics with synthetic biology
Nature Reviews Drug Discovery, 2021Andres Cubillos-Ruiz +2 more
exaly
Synthetic Antigens and Vaccines
1989Early studies in our laboratory have demonstrated that synthetic antigens containing an immunoreactive region of a protein can give rise to a specific, and often conformation-dependent, immune response towards the intact native protein (Arnon et al, 1971). When the protein in question is a component of a virus e.g.
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The Production and Characterization of Synthetic Glycoconjugate Vaccines
Chemical conjugation of polysaccharides to protein carriers has become essential in carbohydrate vaccine development to enhance the poor immunogenicity of glycans. Neutral and uncharged carbohydrates induce T-cell independent responses, failing to produce robust IgG antibodies or sustained T-cell memory and conjugating native or synthetic glycans with ...Aina, Valenti +2 more
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Development of Synthetic Vaccines
1993The development of vaccines has been one of the most important achievements in immunology and medicine to date. It was initiated almost two hundred years ago, by the famous trial of Jenner, who inoculated a small boy with cow pox, thereby achieving preventive immunity against the fatal small pox, a process which eventually led to the eradication of ...
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