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Nanoparticles as synthetic vaccines
Current Opinion in Biotechnology, 2015As vaccines have transitioned from the use of whole pathogens to only the required antigenic epitopes, unwanted side effects have been decreased, but corresponding immune responses have been greatly diminished. To enhance immunogenicity, a variety of controlled release vehicles have been proposed as synthetic vaccines, but nanoparticles have emerged as
Josiah D, Smith +2 more
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Scientific American, 1983
Synthetic vaccines are designed with the help of computer-graphics programs. These displays generated by Arthur J. Olson of the Research Institute of Scripps Clinic show a method whereby parts of a viral protein that are on the surface of a virus, and therefore accessible to antibodies, can be identified.
R, Arnon, M, Shapira, C O, Jacob
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Synthetic vaccines are designed with the help of computer-graphics programs. These displays generated by Arthur J. Olson of the Research Institute of Scripps Clinic show a method whereby parts of a viral protein that are on the surface of a virus, and therefore accessible to antibodies, can be identified.
R, Arnon, M, Shapira, C O, Jacob
openaire +4 more sources
Emerging advances in synthetic cancer nano-vaccines: opportunities and challenges
Expert Review of Vaccines, 2020Introduction: Cancer immunotherapy is a fast-growing field that has achieved tremendous progress in recent years. It is one of the most potent tools that can activate the immune system against cancer.
M. Ahmad +5 more
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Synthetic peptides as vaccines
Current Opinion in Immunology, 1992The use of synthetic peptides as an alternative approach to vaccination is currently being pursued. This is particularly true for viral and parasitic diseases in which no vaccines are yet available, most notably the acquired immune deficiency syndrome.
R, Arnon, R J, Horwitz
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Biological Chemistry, 2001
Although vaccines have proven very successful in preventing certain infectious diseases, progress in the field has been slowed by the tediousness of developing classical vaccines consisting of whole pathogens. Thus, there is great need for improvement in several areas: firstly, the range of diseases which can be treated has to be expanded.
W, Zauner +4 more
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Although vaccines have proven very successful in preventing certain infectious diseases, progress in the field has been slowed by the tediousness of developing classical vaccines consisting of whole pathogens. Thus, there is great need for improvement in several areas: firstly, the range of diseases which can be treated has to be expanded.
W, Zauner +4 more
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Synthetic Peptides as Vaccines
Nature, 1987The economics of vaccines has been a major limitation in the commercial research and development of new approaches. This coupled with the natural scientific desire to simplify and define the composition of effective vaccines argues that the future of vaccines lies in novel approaches that will discover effective and less expensive components. Peptides,
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The design of semi-synthetic and synthetic glycoconjugate vaccines
Expert Opinion on Drug Discovery, 2011Glycoconjugate vaccines are among the safest and most efficacious vaccines developed during the last 30 years. They are a potent tool for prevention of life-threatening bacterial infectious diseases like meningitis and pneumonia. The concept of hapten-carrier conjugation is now being extended to other disease areas.This is an overview of the history ...
Paolo, Costantino +2 more
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Annual Review of Microbiology, 1984
INTRODUCTION...... ..... 221 Vaccines in the Control of Virus Diseases .....
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INTRODUCTION...... ..... 221 Vaccines in the Control of Virus Diseases .....
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