Results 11 to 20 of about 59,490 (287)
Norwalk virus-like particles as vaccines [PDF]
Expert Review of Vaccines, 2010 Noroviruses (NoV) cause the great majority of epidemic nonbacterial gastroenteritis in humans. Expression of the capsid protein in recombinant systems, including insect and plant cells, yields assembly of virus-like particles (VLPs) that mimic the antigenic structure of authentic virions, and are relatively acid- and heat-stable.
Melissa, Herbst-Kralovetz +2 more
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COVID-19 vaccine and immune response
Exploration of Immunology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; βCoV), the causative agent of coronavirus disease 2019 (COVID-19), causes severe lower respiratory tract infections and acute respiratory failure syndrome (ARDS).
Sevilay Hintistan, Hatice Demirağ
doaj +1 more source
Few and Far Between: How HIV May Be Evading Antibody Avidity [PDF]
, 2010 No ...
Bjorkman, Pamela J., Klein, Joshua S.
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Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines
Frontiers in Immunology, 2020 Prophylactic vaccines remain the best approach for controlling the human immunodeficiency virus-1 (HIV-1) transmission. Despite the limited efficacy of the RV144 trial in Thailand, there is still no vaccine candidate that has been proven successful ...
Chun-Wei Chen +5 more
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Evaluation of electrospray differential mobility analysis for virus particle analysis: Potential applications for biomanufacturing. [PDF]
, 2011 The technique of electrospray differential mobility analysis (ES-DMA) was examined as a potential potency assay for routine virus particle analysis in biomanufacturing environments (e.g., evaluation of vaccines and gene delivery products for lot release)
Brorson, Kurt A +4 more
core +1 more source
Ebola Virus Disease Vaccines: Development, Current Perspectives & Challenges
Vaccines, 2023 The global outgoing outbreaks of Ebola virus disease (EVD) in different regions of Sudan, Uganda, and Western Africa have brought into focus the inadequacies and restrictions of pre-designed vaccines for use in the battle against EVD, which has affirmed ...
Sumira Malik +11 more
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Communications Biology, 2022 Cryo-EM structures reveal the role of glutathione (GSH) in poliovirus (PV) serotype 3 virus-like particle (VLP) stability, suggesting GSH or an analogous tight-binding antiviral offers potential for stabilizing VLP vaccines against PV.
Mohammad W. Bahar +10 more
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Recent Advances in the Development of Virus-Like Particle-Based Flavivirus Vaccines
Vaccines, 2020 Flaviviruses include several medically important viruses, such as Zika virus (ZIKV), Dengue virus (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV).
Naru Zhang +3 more
doaj +1 more source
Virus‐like particles for vaccination against cancer [PDF]
WIREs Nanomedicine and Nanobiotechnology, 2019 AbstractActive immunotherapy of cancer aims to treat the disease by inducing effective cellular and humoral immune responses. Virus‐like particle‐based vaccines have evolved dramatically over the last few decades, greatly reducing morbidity and mortality of several infectious diseases and expectedly preventing cervical cancer caused by human papilloma ...
Mona O. Mohsen +3 more
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Virus-like particles as universal influenza vaccines [PDF]
Expert Review of Vaccines, 2012 Current influenza vaccines are primarily targeted to induce immunity to the influenza virus strain-specific hemagglutinin antigen and are not effective in controlling outbreaks of new pandemic viruses. An approach for developing universal vaccines is to present highly conserved antigenic epitopes in an immunogenic conformation such as virus-like ...
Sang-Moo, Kang +2 more
openaire +2 more sources