Results 11 to 20 of about 59,754 (305)
Virus-like particle vaccines: immunology and formulation for clinical translation
Expert Review of Vaccines, 2018 Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation from laboratory models, to routine clinical administration. While some VLP vaccines thrive and are readily adopted into the vaccination schedule, others are
Braeden Donaldson +4 more
doaj +2 more sources
Norwalk virus-like particles as vaccines [PDF]
Expert Review of Vaccines, 2010 Noroviruses (NoV) cause the great majority of epidemic nonbacterial gastroenteritis in humans. Expression of the capsid protein in recombinant systems, including insect and plant cells, yields assembly of virus-like particles (VLPs) that mimic the antigenic structure of authentic virions, and are relatively acid- and heat-stable.
Melissa, Herbst-Kralovetz +2 more
openaire +2 more sources
Iranian Journal of Allergy, Asthma and Immunology, 2021 The widespread outbreak of coronavirus disease 2019 in late 2019 caused many people worldwide to die or suffer from certain clinical complications even after the recovery. The virus has many social and economic adverse effects.
Afshin Abdi Ghavidel +3 more
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COVID-19 vaccine and immune response
Exploration of Immunology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; βCoV), the causative agent of coronavirus disease 2019 (COVID-19), causes severe lower respiratory tract infections and acute respiratory failure syndrome (ARDS).
Sevilay Hintistan, Hatice Demirağ
doaj +1 more source
Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines
Frontiers in Immunology, 2020 Prophylactic vaccines remain the best approach for controlling the human immunodeficiency virus-1 (HIV-1) transmission. Despite the limited efficacy of the RV144 trial in Thailand, there is still no vaccine candidate that has been proven successful ...
Chun-Wei Chen +5 more
doaj +1 more source
Evaluation of electrospray differential mobility analysis for virus particle analysis: Potential applications for biomanufacturing. [PDF]
, 2011 The technique of electrospray differential mobility analysis (ES-DMA) was examined as a potential potency assay for routine virus particle analysis in biomanufacturing environments (e.g., evaluation of vaccines and gene delivery products for lot release)
Brorson, Kurt A +4 more
core +1 more source
Epitope-Specific Anti-hCG Vaccines on a Virus Like Particle Platform.
PLoS ONE, 2015 The possibility of a contraceptive vaccine targeting human chorionic gonadotropin has long been recognized, but never fully realized. Here we describe an epitope-specific approach based on immunogenic display of hCG-derived peptides on virus-like ...
Jerri Caldeira +4 more
doaj +1 more source
Ebola Virus Disease Vaccines: Development, Current Perspectives & Challenges
Vaccines, 2023 The global outgoing outbreaks of Ebola virus disease (EVD) in different regions of Sudan, Uganda, and Western Africa have brought into focus the inadequacies and restrictions of pre-designed vaccines for use in the battle against EVD, which has affirmed ...
Sumira Malik +11 more
doaj +1 more source
Human papillomavirus and HPV vaccines: a review [PDF]
, 2007 Cervical cancer, the most common cancer affecting women in developing countries, is caused by persistent infection with "high-risk" genotypes of human papillomaviruses (HPV). The most common oncogenic HPV genotypes are 16 and 18, causing approximately 70%
Castellsague, X. +10 more
core +3 more sources
Communications Biology, 2022 Cryo-EM structures reveal the role of glutathione (GSH) in poliovirus (PV) serotype 3 virus-like particle (VLP) stability, suggesting GSH or an analogous tight-binding antiviral offers potential for stabilizing VLP vaccines against PV.
Mohammad W. Bahar +10 more
doaj +1 more source