Results 1 to 10 of about 76,843 (254)

An Update on the Known Host Range of the Brazilian Vaccinia Virus: An Outbreak in Buffalo Calves

open access: yesFrontiers in Microbiology, 2019
Even nearly forty years after the eradication of smallpox, members of the Poxviridae family continue to be the focus of an increasing number of studies.
Mauricio Teixeira Lima   +7 more
doaj   +2 more sources

Vaccinia virus-based vector against infectious diseases and tumors

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Vaccinia virus was used to prevent smallpox. After the World Health Organization declared smallpox extinct, vaccinia virus has been explored for the development of vaccines against a variety of infectious diseases.
Ziling Zhang   +5 more
doaj   +2 more sources

Differences in Mpox and Vaccinia Immunity Induced by Non-Replicating and Replicating Vaccinia-Based Vaccines [PDF]

open access: yesVaccines
Background: The recent global outbreak with clade IIb and the concurrent emergence of clade I mpox virus in Africa show that mpox is a challenging problem. MVA-BN induces low-level mpox-neutralizing antibody responses that wane rapidly.
Getahun Abate   +7 more
doaj   +2 more sources

Whence Feral Vaccinia?

open access: yesEmerging Infectious Diseases, 2010
When the World Health Organization declared smallpox eradicated in 1979, smallpox vaccination was discontinued worldwide. Although cessation of smallpox vaccination is well justified, given the risks associated with complications from the vaccine, lack of vaccination nevertheless creates a growing population of persons now susceptible to infection by a
Richard C. Condit
doaj   +4 more sources

The Life Cycle of the Vaccinia Virus Genome.

open access: yesAnnual Review of Virology, 2022
Poxviruses, of which vaccinia virus is the prototype, are a large family of double-stranded DNA viruses that replicate exclusively in the cytoplasm of infected cells.
Matthew D. Greseth, P. Traktman
semanticscholar   +1 more source

Vaccinia-Virus-Based Vaccines Are Expected to Elicit Highly Cross-Reactive Immunity to the 2022 Monkeypox Virus

open access: yesViruses, 2022
Beginning in May 2022, a novel cluster of monkeypox virus infections was detected in humans. This virus has spread rapidly to non-endemic countries, sparking global concern.
Syed Faraz Ahmed   +3 more
semanticscholar   +1 more source

pH Sensitive Erythrocyte-Derived Membrane for Acute Systemic Retention and Increased Infectivity of Coated Oncolytic Vaccinia Virus

open access: yesPharmaceutics, 2022
Oncolytic viruses have emerged as a promising modality in cancer treatment given their high synergy with highly efficient immune checkpoint inhibitors. However, their potency is limited by their rapid in vivo clearance.
Kaelan T. Samoranos   +9 more
doaj   +1 more source

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