Results 1 to 10 of about 56,773 (216)
Emerging Infectious Diseases, 2010 When the World Health Organization declared smallpox eradicated in 1979, smallpox vaccination was discontinued worldwide. Although cessation of smallpox vaccination is well justified, given the risks associated with complications from the vaccine, lack of vaccination nevertheless creates a growing population of persons now susceptible to infection by a
Richard C. Condit
doaj +3 more sources
Differences in Mpox and Vaccinia Immunity Induced by Non-Replicating and Replicating Vaccinia-Based Vaccines [PDF]
VaccinesBackground: The recent global outbreak with clade IIb and the concurrent emergence of clade I mpox virus in Africa show that mpox is a challenging problem. MVA-BN induces low-level mpox-neutralizing antibody responses that wane rapidly.
Getahun Abate +7 more
doaj +2 more sources
Pharmaceutics, 2022 Oncolytic viruses have emerged as a promising modality in cancer treatment given their high synergy with highly efficient immune checkpoint inhibitors. However, their potency is limited by their rapid in vivo clearance.
Kaelan T. Samoranos +9 more
doaj +1 more source
Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses
Frontiers in Immunology, 2020 We conducted a large genome-wide association study (GWAS) of the immune responses to primary smallpox vaccination in a combined cohort of 1,653 subjects.
Richard B. Kennedy +8 more
doaj +1 more source
Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research
Microorganisms, 2022 Amidst the ongoing monkeypox outbreak, global awareness has been directed towards the prevention of viral transmission and case management, with the World Health Organization declaring the outbreak a public health emergency of international concern ...
Tolulope Fashina +4 more
doaj +1 more source
The Rise and Fall of Modern Plagues
Molecular Frontiers Journal, 2020 Millennia separate smallpox, the oldest pandemic, and COVID-19, the newest. Both calamities arose from an opportunistic virus amid human crowding. A vaccine for smallpox existed since the late 18th century, but it took worldwide public health strategy to
G. Terry Sharrer
doaj +1 more source
Clinical Infectious Diseases, 2003 The resumption of smallpox vaccination for health care workers and other first responders has raised concern about the occurrence of complications in people with immunodeficiency disorders, including those infected with human immunodeficiency virus.
Mike, Bray, Mary E, Wright
openaire +2 more sources
In situ cryo-electron tomography of vaccinia virus exit from infected cells [PDF]
Hernandez-Gonzalez M +4 more
europepmc +2 more sources
Frontiers in Immunology, 2021 Respiratory syncytial virus (RSV) is a leading cause of respiratory infections worldwide and disease management measures are hampered by the lack of a safe and effective vaccine against the infection.
Marsha S. Russell +18 more
doaj +1 more source
When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond
Journal of Infection in Developing Countries, 2008 The presence of zoonotic poxviruses in nature represents a potential human health risk that has to be re-evaluated by health authorities not only in developing countries, but also in many developed countries.
Nissin Moussatché,1,2 Clarissa R. Damaso,2 and Grant McFadden1
doaj +3 more sources