Results 11 to 20 of about 96,968 (259)
Viruses, 2023 The ongoing global Monkeypox outbreak that started in the spring of 2022 has reinforced the importance of protecting the population using live virus vaccines based on the vaccinia virus (VACV).
Ryan S. Noyce +10 more
doaj +1 more source
Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?
Emerging Infectious Diseases, 2011 In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj +1 more source
Role of early viral surface antigens in cellular immune response to vaccinia virus [PDF]
, 1976 Infection of mice with the vaccinia virus strain WR, Elstree or DIs, a conditional lethal mutant of vaccinia virus, resulted in the generation of vaccinia virus-specific sensitized cytolytic T lymphocytes (CTL).
Ertl, H., Koszinowski, Ulrich H.
core +1 more source
Secondary and Tertiary Transmission of Vaccinia Virus from US Military Service Member
Emerging Infectious Diseases, 2011 During February and March 2010, the New York State Department of Health investigated secondary and tertiary vaccinia contact transmission from a military vaccinee to 4 close contacts.
Gregory E. Young +10 more
doaj +1 more source
Frontiers in Immunology, 2023 Natural killer (NK) cells have an established role in controlling poxvirus infection and there is a growing interest to exploit their capabilities in the context of poxvirus-based oncolytic therapy and vaccination.
Delphine M. Depierreux +2 more
doaj +1 more source
Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]
, 1975 The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
A. V. Boand +25 more
core +1 more source
Retrospective Analysis of Monkeypox Infection
Emerging Infectious Diseases, 2008 Serologic cross-reactivity between orthopoxviruses is a substantial barrier to laboratory diagnosis of specific orthopoxvirus infections and epidemiologic characterization of disease outbreaks.
Melissa E. Dubois, Mark K. Slifka
doaj +1 more source
Neutralization Determinants on Poxviruses
Viruses, 2023 Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
doaj +1 more source
Recombinant Poxvirus and the Tumor Microenvironment: Oncolysis, Immune Regulation and Immunization
Biomedicines, 2016 Oncolytic viruses (OVs) are being extensively studied for their potential roles in the development of cancer therapy regimens. In addition to their direct lytic effects, OVs can initiate and drive systemic antitumor immunity indirectly via release of ...
Daniel W. Sharp, Edmund C. Lattime
doaj +1 more source
Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
, 1975 Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan +36 more
core +1 more source