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Remaining Questions about Clinical Variola Major
Emerging Infectious Diseases, 2011 After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
doaj +1 more source
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors [PDF]
, 2010 Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV.
Atkins, H +15 more
core +1 more source
Lysis mediated by T cells and restricted by H-2 antigen of target cells infected with vaccinia virus [PDF]
, 1975 VARIOUS virus infections lead to the formation of cytotoxic lymphocytes (CL), which are capable of killing virus-infected target cells1−4. Specific lysis of target cells infected with 51Cr-labelled vaccinia virus could be observed when investigating the ...
GJ Hämmerling +13 more
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Mass Smallpox Vaccination and Cardiac Deaths, New York City, 1947
Emerging Infectious Diseases, 2004 In April 1947, during a smallpox outbreak in New York City (NYC), >6,000,000 people were vaccinated. To determine whether vaccination increased cardiac death, we reviewed NYC death certificates for comparable periods in 1946 and 1948 (N = 81,529) and ...
Lorna E. Thorpe +6 more
doaj +1 more source
Studies on processing, particle formation, and immunogenicity of the HIV-1 gag gene product: a possible component of a HIV vaccine [PDF]
, 1992 Antigens in a particulate conformation were shown to be highly immunogenic in mammals. For this reason, the particle forming capacity of derivatives of the HIV-1 group specific core antigen p55 gag was assayed and compared dependent on various expression
Deby, G. +7 more
core +1 more source
The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility [PDF]
, 2013 Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs).
Alberts +79 more
core +2 more sources
JAMA: The Journal of the American Medical Association, 1907 In an experience with smallpox limited to the town of Colorado and occurring between the dates of April 7 and May 20, 1907, the following conditions were encountered. They are interesting as confirming previous observations as to the coincidence of variola and vaccinia.
openaire +2 more sources