Results 21 to 30 of about 76,843 (254)
Challenges and Achievements in Prevention and Treatment of Smallpox
Vaccines, 2018 Declaration of smallpox eradication by the WHO in 1980 led to discontinuation of the worldwide vaccination campaign. The increasing percentage of unvaccinated individuals, the existence of its causative infectious agent variola virus (VARV), and the ...
Sharon Melamed, Tomer Israely, Nir Paran
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Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox.
New England Journal of Medicine, 2019 BACKGROUND Many countries have stockpiled vaccines because of concerns about the reemergence of smallpox. Traditional smallpox vaccines are based on replicating vaccinia viruses; these vaccines have considerable side effects.
P. Pittman +12 more
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Journal of Virology, 2019 Viruses rely on their infected host cells to provide nutrients and energy for replication. Vaccinia virus, the prototypic member of the poxviruses, which comprise many significant human and animal pathogens, prefers glutamine to glucose for efficient ...
Anil Pant, Shuai Cao, Zhilong Yang
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The Virology of Taterapox Virus In Vitro
Viruses, 2018 Taterapox virus (TATV) is phylogenetically the closest related virus to variola—the etiological agent of smallpox. Despite the similarity, few studies have evaluated the virus.
Scott Parker +8 more
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Journal of Virology, 2018 African swine fever virus (ASFV) causes an acute hemorrhagic fever in domestic pigs, with high socioeconomic impact. No vaccine is available, limiting options for control.
J. Jancovich +14 more
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Nature Microbiology, 2018 Cell motility is essential for viral dissemination1. Vaccinia virus (VACV), a close relative of smallpox virus, is thought to exploit cell motility as a means to enhance the spread of infection1.
Corina Beerli +7 more
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OncoImmunology, 2017 A heavily pretreated patient with triple negative breast cancer distinguished by cutaneous metastases received p53MVA vaccine in combination with pembrolizumab.
Yuan Yuan +11 more
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Remaining Questions about Clinical Variola Major
Emerging Infectious Diseases, 2011 After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
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Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research
Microorganisms, 2022 Amidst the ongoing monkeypox outbreak, global awareness has been directed towards the prevention of viral transmission and case management, with the World Health Organization declaring the outbreak a public health emergency of international concern ...
Tolulope Fashina +4 more
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