Results 21 to 30 of about 98,253 (278)

Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]

, 2010
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M., Carter, P. E., Collins-Emerson, J. M., French, N. P., Hathaway, S., Marshall, J., Midwinter, A. C., Mullner, P., Pirie, R., Shadbolt, T., Spencer, Simon E. F., Wilson, D. J.   +11 more
core   +1 more source

Remaining Questions about Clinical Variola Major

Emerging Infectious Diseases, 2011
After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
doaj   +1 more source

The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility [PDF]

, 2013
Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs).
Alberts, Alvarez, Arakawa, Bagrodia, Bernardini, Block, Boujemaa-Paterski, Chong, Chong, Diego E. Alvarez, Earl, Engelstad, Feig, Frischknecht, Fukuoka, Gasteier, Goldberg, Haglund, Hannemann, Harris, Harris, Heindl, Hervé Agaisse, Hiller, Hollinshead, Hoppe, Humphries, Isaacs, Katz, Kleba, Koka, Kovar, Krall, Lammers, Lasa, Li, Madrid, Moseley, Moseley, Newsome, Newsome, Nezami, Otomo, Parkinson, Pollard, Pring, Pruyne, Qiu, Ridley, Rietdorf, Roberts, Rolls, Romero, Röttger, Sanderson, Scaplehorn, Schmelz, Schulte, Schönichen, Schönichen, Serio, Shibata, Siripala, Skoble, Smith, Suzuki, Takeya, Tooze, van Eijl, van Eijl, Wallar, Ward, Ward, Watanabe, Weisswange, Welch, Westendorf, Westendorf, Wolffe, Wolffe   +79 more
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Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab

OncoImmunology, 2017
A heavily pretreated patient with triple negative breast cancer distinguished by cutaneous metastases received p53MVA vaccine in combination with pembrolizumab.
Yuan Yuan, Ferdynand J. Kos, Ting-Fang He, Hongwei H. Yin, Mengsha Li, Nicola Hardwick, Kathryn Zurcher, Daniel Schmolze, Peter Lee, Raju K. Pillai, Vincent Chung, Don J. Diamond   +11 more
doaj   +1 more source

Lysis mediated by T cells and restricted by H-2 antigen of target cells infected with vaccinia virus [PDF]

, 1975
VARIOUS virus infections lead to the formation of cytotoxic lymphocytes (CL), which are capable of killing virus-infected target cells1−4. Specific lysis of target cells infected with 51Cr-labelled vaccinia virus could be observed when investigating the ...
GJ Hämmerling, GM Shearer, H. ERTL, HR McFarland, I Gardner, LF Speel, M Nabholz, M Schlesinger, O Marker, RM Zinkernagel, RM Zinkernagel, RM Zinkernagel, RV Blanden, U. KOSZINOWSKI   +13 more
core   +1 more source

Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion [PDF]

, 2005
Type IB DNA topoisomerases cleave and rejoin one strand of the DNA duplex, allowing for the removal of supercoils generated during replication and transcription.
Dekker, Cees, Dekker, Nynke H., Holtzer, Laurent, Koster, Daniel A., Moreno-Herrero, Fernando, Shuman, Stewart   +5 more
core   +2 more sources

Retrospective Analysis of Monkeypox Infection

Emerging Infectious Diseases, 2008
Serologic cross-reactivity between orthopoxviruses is a substantial barrier to laboratory diagnosis of specific orthopoxvirus infections and epidemiologic characterization of disease outbreaks.
Melissa E. Dubois, Mark K. Slifka
doaj   +1 more source

Recombinant Poxvirus and the Tumor Microenvironment: Oncolysis, Immune Regulation and Immunization

Biomedicines, 2016
Oncolytic viruses (OVs) are being extensively studied for their potential roles in the development of cancer therapy regimens. In addition to their direct lytic effects, OVs can initiate and drive systemic antitumor immunity indirectly via release of ...
Daniel W. Sharp, Edmund C. Lattime
doaj   +1 more source

The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]

, 1991
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Münch, Konrad   +3 more
core   +1 more source

Mass Smallpox Vaccination and Cardiac Deaths, New York City, 1947

Emerging Infectious Diseases, 2004
In April 1947, during a smallpox outbreak in New York City (NYC), >6,000,000 people were vaccinated. To determine whether vaccination increased cardiac death, we reviewed NYC death certificates for comparable periods in 1946 and 1948 (N = 81,529) and ...
Lorna E. Thorpe, Farzad Mostashari, Adam M. Karpati, Steven P. Schwartz, Susan E. Manning, Melissa A. Marx, Thomas R. Frieden   +6 more
doaj   +1 more source