Results 91 to 100 of about 1,739,286 (305)

Generation of recombinant vaccinia virus and analysis of virus-induced cell death

STAR Protocols, 2021
Summary: Vaccinia virus is a large double-stranded DNA virus that is widely used to express foreign genes from different origins. We generated recombinant vaccinia virus that expresses a viral inhibitor to examine its effect on virus-induced necroptosis.
Zhijun Liu, Kidong Kang, Francis Ka-Ming Chan   +2 more
doaj  

Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques.

Molecular Therapy, 2015
Oncolytic viruses (OVs) have shown promising clinical activity when administered by direct intratumoral injection. However, natural barriers in the blood, including antibodies and complement, are likely to limit the ability to repeatedly administer OVs ...
Laura Evgin, S. Acuna, C. Tanese de Souza, M. Marguerie, Chantal G. Lemay, C. Ilkow, C. Findlay, T. Falls, K. Parato, David Hanwell, Alyssa Goldstein, Roberto Lopez, Sandra Lafrance, C. Breitbach, D. Kirn, H. Atkins, R. Auer, J. Thurman, G. Stahl, John D Lambris, J. Bell, J. McCart   +21 more
semanticscholar   +1 more source

Does limited virucidal activity of biocides include duck hepatitis B virucidal action? [PDF]

, 2012
BACKGROUND: There is agreement that the infectivity assay with the duck hepatitis B virus (DHBV) is a suitable surrogate test to validate disinfectants for hepatitis B virucidal activity.
Bust, Uwe, Glück, Brigitte, Rabenau, Holger, Sauerbrei, Andreas, Schacke, Michael, Wutzler, Peter   +5 more
core   +1 more source

Inclusion Bodies of the Vaccinia Virus.

Experimental Biology and Medicine, 1958
SummaryTwo kinds of inclusion bodies, “A” and “B” type, exist in tissues infected with ectromelia, fowl pox and vaccinia viruses. “B” type inclusion bodies of these 3 pox group viruses have almost the same morphological and cytochemical characters. The “A” type inclusion bodies of these viruses differ according to virus and host cell.
Shiro Kato, Kiichi Hagiwara, Yotaro Sato, Juntaro Kamahora   +3 more
openaire   +3 more sources

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, EarlyView.
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary, Lucky Lucky, Harsh Sable, Nikhil Bhalla   +3 more
wiley   +1 more source

A novel high-throughput vaccinia virus neutralization assay and preexisting immunity in populations from different geographic regions in China. [PDF]

PLoS ONE, 2012
BACKGROUND: Pre-existing immunity to Vaccinia Tian Tan virus (VTT) resulting from a large vaccination campaign against smallpox prior to the early 1980s in China, has been a major issue for application of VTT-vector based vaccines.
Qiang Liu, Weijin Huang, Jianhui Nie, Rong Zhu, Dongying Gao, Aijing Song, Shufang Meng, Xuemei Xu, Youchun Wang   +8 more
doaj   +1 more source

Proliferative and neoplastic aural pinna masses in a collection of African giant pouched rats (Cricetomys ansorgei)

Veterinary Record Case Reports, EarlyView.
Abstract This case series describes aural lesions occurring in five African giant pouched rats (Cricetomys ansorgei) residing at a single zoological institution in southern California. Age of onset ranged from 3 to 7 years. Lesions occurred as single or multiple masses on one or both ears. A single case also developed a nasal mass.
Amanda Burke, Alison Righton, Tess Rooney, Matt Marinkovich, Garrett Fraess   +4 more
wiley   +1 more source

Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion [PDF]

, 2005
Type IB DNA topoisomerases cleave and rejoin one strand of the DNA duplex, allowing for the removal of supercoils generated during replication and transcription.
Dekker, Cees, Dekker, Nynke H., Holtzer, Laurent, Koster, Daniel A., Moreno-Herrero, Fernando, Shuman, Stewart   +5 more
core   +2 more sources

Application of poxvirus K3 ortholog as a positive selection marker for constructing recombinant vaccinia viruses with modified host range

MethodsX, 2020
Vaccinia virus is capable of replicating in a wide range of vertebrate animal cells. However, deletion of the two virus host range genes, E3L and K3L, would render replication of the virus abortive in all the cell types tested, except the cells with ...
Jingxin Cao, Christine Layne, Jessie Varga, Yvon Deschambault   +3 more
doaj  

Ocular Vaccinia Infection in Dairy Worker, Brazil

Emerging Infectious Diseases, 2018
We studied a clinical case of vaccinia virus that caused an ocular manifestation in a dairy worker in Brazil. Biologic and molecular analyses identified a co-infection with 2 isolates from different Brazilian vaccinia virus phylogenetic groups.
Maurício Teixeira Lima, Graziele Pereira Oliveira, Felipe Lopes Assis, Danilo Bretas de Oliveira, Sidiner Mesquita Vaz, Giliane de Souza Trindade, Jônatas Santos Abrahão, Erna Geessien Kroon   +7 more
doaj   +1 more source