Results 111 to 120 of about 1,739,286 (305)
Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.Lumpy Skin Disease: A notifiable transboundary disease caused by the lumpy skin disease virus (LSDV), under the Poxviridae family, causing nodular skin lesions with major economic impact on livestock, transmitted through blood sucking arthropods.
F. M. Yasir Hasib, Md. Shafiqul Islam
wiley +1 more source
Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles [PDF]
, 2011 Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial.
Anson, Donald S. +9 more
core +4 more sources
iMetaOmics, Volume 2, Issue 2, June 2025.Botswana's Seronga region saw a mass elephant die‐off potentially linked to water sources. This study analyzes Okavango Delta metagenomes, uncovering a diversity of viruses and harmful pathogens. Findings highlight the importance of understanding viral ecology in these waters and support One Health's objective in protecting human, animal, and ecosystem
Emilie J. Skoog +8 more
wiley +1 more source
Serological Immunity to Smallpox in New South Wales, Australia
Viruses, 2020 The re-emergence of smallpox is an increasing and legitimate concern due to advances in synthetic biology. Vaccination programs against smallpox using the vaccinia virus vaccine ceased with the eradication of smallpox and, unlike many other countries ...
Valentina Costantino +5 more
doaj +1 more source
PLoS Pathogens, 2023 Host cell entry of vaccinia virus (a poxvirus) proceeds through multiple steps that involve many viral proteins to mediate cell infection. Upon binding to cells, vaccinia virus membrane fuses with host membranes via a viral entry fusion protein complex ...
Chi-Fei Kao +4 more
doaj +1 more source
Clinical Cancer Research, 2014 Purpose: Vaccinia virus has strong potential as a novel therapeutic agent for treatment of pancreatic cancer. We investigated whether arming vaccinia virus with interleukin-10 (IL10) could enhance the antitumor efficacy with the view that IL10 might ...
Louisa S. Chard +16 more
semanticscholar +1 more source
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, Volume 14, Issue 14, May 28, 2025.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
BioTechniques, 2002 Recombinant vaccinia virus is a useful and powerful tool for the expression and study of foreign genes. Methods that are currently available for the selection of vaccinia virus recombinants include the restoration of viral plaque-forming phenotype, the ...
Scott G. Hansen +2 more
doaj +1 more source
Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans.
Cancer Research, 2013 Efforts to selectively target and disrupt established tumor vasculature have largely failed to date. We hypothesized that a vaccinia virus engineered to target cells with activation of the ras/MAPK signaling pathway (JX-594) could specifically infect and
C. Breitbach +17 more
semanticscholar +1 more source
Viral metagenomic analysis reveals potential biological hazards in non‐human primates in a zoo
Animal Research and One Health, Volume 3, Issue 2, Page 217-228, May 2025.The investigation identifies the presence of Encephalomyocarditis virus (EMCV), Baboon endogenous virus (BAV), Human endogenous retrovirus (HERV), and Baboon endogenous virus (BaEV) in non‐human primates (NHPs) at the Zoo, indicating potential zoonotic threats.
Ruiying Liang +13 more
wiley +1 more source