Results 111 to 120 of about 1,775,772 (324)

A Vaccinia Virus Armed with Interleukin-10 Is a Promising Therapeutic Agent for Treatment of Murine Pancreatic Cancer

open access: yesClinical Cancer Research, 2014
Purpose: Vaccinia virus has strong potential as a novel therapeutic agent for treatment of pancreatic cancer. We investigated whether arming vaccinia virus with interleukin-10 (IL10) could enhance the antitumor efficacy with the view that IL10 might ...
Louisa S. Chard   +16 more
semanticscholar   +1 more source

Safety and Efficacy of Plant‐Produced Trivalent Virus‐Like Particle Vaccine Candidate Against Bluetongue Disease

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Bluetongue (BT) is a non‐contagious, insect‐transmitted disease of wild and domestic ruminants caused by bluetongue virus (BTV). Effective control of BT disease relies on vaccination against prevalent or seasonal serotypes using live attenuated or inactivated vaccines.
Tendai A. M. Mlingo   +8 more
wiley   +1 more source

The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]

open access: yes, 1991
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard   +3 more
core   +1 more source

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics

open access: yesMedComm, Volume 7, Issue 1, January 2026.
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan   +14 more
wiley   +1 more source

BiZyme: A Novel Fusion Protein-Mediating Selection of Vaccinia Virus Recombinants by Fluorescence and Antibiotic Resistance

open access: yesBioTechniques, 2002
Recombinant vaccinia virus is a useful and powerful tool for the expression and study of foreign genes. Methods that are currently available for the selection of vaccinia virus recombinants include the restoration of viral plaque-forming phenotype, the ...
Scott G. Hansen   +2 more
doaj   +1 more source

Serological Immunity to Smallpox in New South Wales, Australia

open access: yesViruses, 2020
The re-emergence of smallpox is an increasing and legitimate concern due to advances in synthetic biology. Vaccination programs against smallpox using the vaccinia virus vaccine ceased with the eradication of smallpox and, unlike many other countries ...
Valentina Costantino   +5 more
doaj   +1 more source

Modification of H-2 Antigenic Sites by Enzymatic Treatment Influences Virus-Specific Target Cell Lysis [PDF]

open access: yes, 1976
Vaccinia virus-infected cells were treated enzymatically to remove H-2 antigenic sites. The effect of this procedure on virus-specific cell-mediated cytolysis (CMC) and virus-specific antibody-mediated cytolysis (AMC) was tested. Due to the inhibition of
Ertl, H., Koszinowski, Ulrich H.
core  

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity.

open access: yesJournal of General Virology, 2013
Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Geoffrey L. Smith   +6 more
semanticscholar   +1 more source

Lack of Transmission of Vaccinia Virus

open access: yesEmerging Infectious Diseases, 2006
To the Editor: Recently, the US government completed a targeted vaccination strategy limited to healthcare workers, first responders, and the military because of concern that variola virus, the etiologic agent of smallpox, might be used as a biowarfare agent (1).
James H. Stark   +3 more
openaire   +3 more sources

Synthesizing current knowledge on the ecology, phenology, and cultivation of Vaccinium membranaceum

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 1, Page 116-133, January 2026.
More than 100 edible native berries grow across Canada's vast territory and are used by over 600 Indigenous Peoples of Canada as a main component of their diet. This research provides critical insights into the ecology, phenology, and cultivation of black huckleberry (Vaccinium membranaceum), a species of significant ecological and cultural importance ...
Mehdi Sharifi   +12 more
wiley   +1 more source

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