Results 11 to 20 of about 1,739,286 (305)

Vaccinia virus-based vector against infectious diseases and tumors

Human Vaccines & Immunotherapeutics, 2021
Vaccinia virus was used to prevent smallpox. After the World Health Organization declared smallpox extinct, vaccinia virus has been explored for the development of vaccines against a variety of infectious diseases.
Ziling Zhang, Lanlan Dong, Chen Zhao, Peiyong Zheng, Xiaoyan Zhang, Jianqing Xu   +5 more
doaj   +2 more sources

An Update on the Known Host Range of the Brazilian Vaccinia Virus: An Outbreak in Buffalo Calves

Frontiers in Microbiology, 2019
Even nearly forty years after the eradication of smallpox, members of the Poxviridae family continue to be the focus of an increasing number of studies.
Mauricio Teixeira Lima, Graziele Pereira Oliveira, José Augusto Bastos Afonso, Rodolfo José Cavancanti Souto, Carla Lopes de Mendonça, Antonio Flavio Medeiros Dantas, Jonatas Santos Abrahao, Erna Geessien Kroon   +7 more
doaj   +2 more sources

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity [PDF]

Journal of General Virology, 2013
Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Benfield, C T O, De Motes, C M, Ember, S W J, Ferguson, B J, Mazzon, M, Smith, G L, Sumner, R P   +6 more
core   +2 more sources

Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors [PDF]

PLoS ONE, 2010
Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV.
Atkins, H, Bell, JC, Breitbach, C, Cox, J, De Silva, N, Diallo, JS, Falls, T, Guimond, T, Huang, B, Kirn, D, Le Boeuf, F, MacTavish, H, McCart, AJ, Simmons, JG, Stanford, M, Thorne, S   +15 more
core   +3 more sources

THE VIRUS OF VACCINIA AND ITS CULTIVATION. [PDF]

The Lancet, 1898
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Amy Kent
openaire   +4 more sources

Outbreak of Severe Zoonotic Vaccinia Virus Infection, Southeastern Brazil

Emerging Infectious Diseases, 2015
In 2010, a vaccinia virus isolate caused an atypically severe outbreak that affected humans and cattle in Brazil. Of 26 rural workers affected, 12 were hospitalized.
Jônatas Santos Abrahão, Rafael Kroon Campos, Giliane de Souza Trindade, Flávio Guimarães da Fonseca, Paulo César Peregrino Ferreira, Maurício Teixeira Lima   +5 more
doaj   +2 more sources

THE PRESERVATION OF VACCINIA VIRUS [PDF]

Bacteriological Reviews, 1954
Leslie Collier
openaire   +4 more sources

Vaccinia-Virus-Based Vaccines Are Expected to Elicit Highly Cross-Reactive Immunity to the 2022 Monkeypox Virus

Viruses, 2022
Beginning in May 2022, a novel cluster of monkeypox virus infections was detected in humans. This virus has spread rapidly to non-endemic countries, sparking global concern.
Syed Faraz Ahmed, M. S. Sohail, A. A. Quadeer, Matthew Mckay   +3 more
semanticscholar   +1 more source

La-related protein 4 is enriched in vaccinia virus factories and is required for efficient viral replication in primary human fibroblasts

Microbiology Spectrum, 2023
In addition to the 3′-poly(A) tail, vaccinia virus mRNAs synthesized after viral DNA replication (post-replicative mRNAs) possess a 5′-poly(A) leader that confers a translational advantage in virally infected cells.
Pragyesh Dhungel, Djamal Brahim Belhaouari, Zhilong Yang   +2 more
doaj   +1 more source

Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes. [PDF]

mBio
Poxviruses comprise pathogens that are highly pathogenic to humans and animals, causing diseases such as smallpox and mpox (formerly monkeypox). The family also contains members developed as vaccine vectors and oncolytic agents to fight other diseases ...
Deng Y, Navarro-Forero S, Yang Z.
europepmc   +2 more sources