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<i>In silico</i> design and experimental validation of a multi-epitope vaccine candidate against <i>Helicobacter hepaticus</i> associated chronic liver inflammation. [PDF]
Front ImmunolWeng L, Huijie Z, Man N, Yang L, Cao M.
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Vaccine Design against <i>Fusobacterium nucleatum</i> FadA Protein in Periodontal Infections. [PDF]
Front DentRathod NN +4 more
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Seminars in Immunology, 2020
The structure and function of the immune system is governed by complex networks of interactions between cells and molecular components. Vaccination perturbs these networks, triggering specific pathways to induce cellular and humoral immunity. Systems vaccinology studies have generated vast data sets describing the genes related to vaccination ...
Helder I Nakaya +2 more
exaly +3 more sources
The structure and function of the immune system is governed by complex networks of interactions between cells and molecular components. Vaccination perturbs these networks, triggering specific pathways to induce cellular and humoral immunity. Systems vaccinology studies have generated vast data sets describing the genes related to vaccination ...
Helder I Nakaya +2 more
exaly +3 more sources
Vaccine, 1984
Vaccinology requires not only an understanding of the fundamental properties of the immune system and specific immunogens, but also the application of basic knowledge to develop effective immunization programmes for particular social, political, and environmental conditions. Two problems exist in the use of oral, live poliovirus vaccine: the occurrence
D, Salk, J, Salk
openaire +2 more sources
Vaccinology requires not only an understanding of the fundamental properties of the immune system and specific immunogens, but also the application of basic knowledge to develop effective immunization programmes for particular social, political, and environmental conditions. Two problems exist in the use of oral, live poliovirus vaccine: the occurrence
D, Salk, J, Salk
openaire +2 more sources
Drug Discovery Today, 2003
Whole-genome sequencing of bacteria and advances in bioinformatics have revolutionized the vaccinology field, leading to the identification of potential vaccine candidates without the need for cultivating the pathogen. This approach, termed "reverse vaccinology", reduces the time and cost required for the identification of candidate vaccines and ...
Marirosa, Mora +4 more
openaire +2 more sources
Whole-genome sequencing of bacteria and advances in bioinformatics have revolutionized the vaccinology field, leading to the identification of potential vaccine candidates without the need for cultivating the pathogen. This approach, termed "reverse vaccinology", reduces the time and cost required for the identification of candidate vaccines and ...
Marirosa, Mora +4 more
openaire +2 more sources
Studies of twins in vaccinology
Vaccine, 2007In this survey, we review published investigations and trials of vaccines among twins. We identified 29 original studies, dating back to 1979. The studies include determinations of the role of genetics and environment in the variation in immune response to vaccination, the investigation of adverse events in which vaccination was the suspected etiologic
Robert M, Jacobson +3 more
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Systems vaccinology studies – achievements and future potential
Microbes and InfectionInternational audienceHuman responses to vaccination are variable both within and between populations. Systems vaccinology, which is the application of multi-omics technologies to vaccine studies, seeks to understand such variation and predict responses ...
Jamie Sugrue, Darragh Duffy
exaly +2 more sources
Reverse Vaccinology and Genomics
Science, 2003The genomic revolution has had a dramatic effect on our ability to find new vaccine targets and develop effective vaccines.
Rino, Rappuoli, Antonello, Covacci
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