Results 171 to 180 of about 23,444 (214)
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Current Opinion in Microbiology, 2000
Biochemical, serological and microbiological methods have been used to dissect pathogens and identify the components useful for vaccine development. Although successful in many cases, this approach is time-consuming and fails when the pathogens cannot be cultivated in vitro, or when the most abundant antigens are variable in sequence.
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Biochemical, serological and microbiological methods have been used to dissect pathogens and identify the components useful for vaccine development. Although successful in many cases, this approach is time-consuming and fails when the pathogens cannot be cultivated in vitro, or when the most abundant antigens are variable in sequence.
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Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1999
Veterinary vaccinology is a very interesting and rapidly developing field. In fact veterinary vaccines are not only used for the prevention of infectious diseases in the animal health sector, but also help to solve problems of public health, to reduce detrimental environmental impact of the use of some veterinary drugs and prevent the emergence of ...
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Veterinary vaccinology is a very interesting and rapidly developing field. In fact veterinary vaccines are not only used for the prevention of infectious diseases in the animal health sector, but also help to solve problems of public health, to reduce detrimental environmental impact of the use of some veterinary drugs and prevent the emergence of ...
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Six Revolutions in Vaccinology
Pediatric Infectious Disease Journal, 2005The history of vaccine development can be divided into 5 waves, produced by revolutions in technology. They are attenuation, inactivation, cell culture of viruses, genetic engineering and methods to induce cellular immune responses. This division is somewhat artificial, and all of the past strategies continue to be useful.
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The promise of reverse vaccinology
International Health, 2015Reverse vaccinology (RV) is a computational approach that aims to identify putative vaccine candidates in the protein coding genome (proteome) of pathogens. RV has primarily been applied to bacterial pathogens to identify proteins that can be formulated into subunit vaccines, which consist of one or more protein antigens.
Ashley I, Heinson +2 more
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Vaccine, 2007
The use of meta-analysis as a method for systematic review of the literature has grown substantially since its appearance in 1988. We obtained and reviewed 134 meta-analyses cited in Current Contents, MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews reporting original meta-analyses in human subjects regarding vaccines directed against ...
Robert M, Jacobson +2 more
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The use of meta-analysis as a method for systematic review of the literature has grown substantially since its appearance in 1988. We obtained and reviewed 134 meta-analyses cited in Current Contents, MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews reporting original meta-analyses in human subjects regarding vaccines directed against ...
Robert M, Jacobson +2 more
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Principles and Practice of Vaccinology
2009Historically, infectious diseases have been a major cause of morbidity and mortality. Improved sanitation and living conditions are thought to have been major factors of the reduction in incidence of infectious diseases in the nineteenth and the early twentieth centuries in most industrialised countries.
Pebody, R, Kretzschmar, M
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Computational Peptide Vaccinology
2014Immunoinformatics focuses on modeling immune responses for better understanding of the immune system and in many cases for proposing agents able to modify the immune system. The most classical of these agents are vaccines derived from living organisms such as smallpox or polio. More modern vaccines comprise recombinant proteins, protein domains, and in
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Recent advances in vaccinology
Current Opinion in Pharmacology, 2001Major advances in vaccinology in the past year include the experimental use of vaccination for diseases such as Alzheimer's and stroke, a demonstration of the power of genomic approaches for target antigen identification, hopeful results in a clinical trial for a therapeutic cancer vaccine, and the successful mass immunisation of children with ...
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Vaccine, 2002
Evidence based vaccinology (EBV) is the identification and use of the best evidence in making and implementing decisions during all of the stages of the life of a vaccine, including pre-licensure vaccine development and post-licensure manufacture and research, and utilization of the vaccine for disease control.
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Evidence based vaccinology (EBV) is the identification and use of the best evidence in making and implementing decisions during all of the stages of the life of a vaccine, including pre-licensure vaccine development and post-licensure manufacture and research, and utilization of the vaccine for disease control.
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Fostering Further Successes in Vaccinology
American Journal of Preventive Medicine, 2015Vaccination—preparing or harnessing the power of the human immune system to prevent infectious diseases—is one of the most impactful developments in the history of public health. In more than two centuries of clinical use, vaccines have been responsible for preserving the health and preventing the deaths of millions of children and adults annually ...
Andrew W, Artenstein +2 more
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