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A cárie dentária é uma das doenças infecciosas mais comum no homem. Um dos principais microrganismos causadores desta doença é o Streptococcus mutans caracterizado pelos seus diversos mecanismos de virulência. Fatores do hospedeiro como consumo elevado de hidratos de carbono e higiene oral deficiente produzem condições ideais na cavidade oral ...
Santos, Joana Gouveia dos
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There is a massive demand to identify alternative methods to detect new cases of COVID-19 as well as to investigate the epidemiology of the disease. In many countries, importation of commercial kits poses a significant impact on their testing capacity ...
Flávia F. Bagno +15 more
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Off balance: Interferons in COVID-19 lung infections
Interferons are innate and adaptive cytokines involved in many biological responses, in particular, viral infections. With the final response the result of the balance of the different types of Interferons.
Milena Apetito Akamatsu +3 more
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Vacinas contra varicela e vacina quádrupla viral [PDF]
OBJETIVOS: Apresentar uma revisao atualizada sobre os estudos de eficacia, eventos adversos e esquema vacinal da vacina contra varicela e a nova apresentacao combinada com a vacina contra sarampo, caxumba e rubeola. FONTES DOS DADOS: Revisao bibliografica utilizando a base de dados MEDLINE e LILACS no periodo de 1999 a 2006. SINTESE DOS DADOS: A vacina
Bricks, Lucia Ferro +2 more
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Vacina Já!
D'Ávila, Otávio Pereira +1 more
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LIC12254 Is a Leptospiral Protein That Interacts with Integrins via the RGD Motif
Pathogenic leptospires can bind to receptors on mammalian cells such as cadherins and integrins. Leptospira effectively adheres to cells, overcomes host barriers and spreads into the bloodstream, reaching internal target organs such as the lungs, liver ...
Maria F. Cavenague +3 more
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An effective immunological response in the lungs during a pneumococcal infection is a key factor to the bacteria clearance and prevention of sepsis. In order to develop broad-range pneumococcal vaccines several pneumococcal proteins and strong adjuvants ...
Cibelly Goulart +4 more
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The current COVID-19 vaccines protect against severe disease, but are not effective in controlling replication of the Variants of Concern (VOCs). Here, we used the existing pre-clinical models of severe and moderate COVID-19 to evaluate the efficacy of a
Patrick O. Azevedo +16 more
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High-risk Human papillomavirus (HPV) infections represent an important public health issue. Nearly all cervical malignancies are associated with HPV, and a range of other female and male cancers, such as anogenital and oropharyngeal.
Roberta Liberato Pagni +13 more
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IntroductionLeptospirosis is a worldwide zoonosis caused by pathogenic and virulent species of the genus Leptospira, whose pathophysiology and virulence factors remain widely unexplored.
Luis G. V. Fernandes +3 more
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