Results 21 to 30 of about 437,206 (353)
Spatiotemporal visualization of subcellular dynamics of carbon nanotubes [PDF]
To date, there is no consensus on the relationship between the physicochemical characteristics of carbon nanotubes (CNTs) and their biological behavior; however, there is growing evidence that the versatile characteristics make their biological fate ...
Baba, Yoshinobu+5 more
core +3 more sources
pH-Dependant Antifungal Activity of Valproic Acid against the Human Fungal Pathogen Candida albicans
Current antifungal drugs suffer from limitations including toxicity, the emergence of resistance and decreased efficacy at low pH that are typical of human vaginal surfaces.
Julien Chaillot+7 more
doaj +1 more source
A microscopy-based kinetic analysis of yeast vacuolar protein sorting
Saccharomyces cerevisiae is amenable to studying membrane traffic by live-cell fluorescence microscopy. We used this system to explore two aspects of cargo protein traffic through prevacuolar endosome (PVE) compartments to the vacuole.
Jason C Casler, Benjamin S Glick
doaj +1 more source
Summary: To maintain secretory pathway fidelity, misfolded proteins are commonly retained in the endoplasmic reticulum (ER) and selected for ER-associated degradation (ERAD).
Zhihao Sun+2 more
doaj +1 more source
Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. [PDF]
Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells, membrane domains regulate membrane dynamics and biochemical and signaling pathways.
Murley, Andrew+6 more
core +1 more source
SUMMARYMany plant cells are characterized by the presence of a vacuole (hypertrophied lysosome) occupying a large fraction of the protoplast. The possible benefits of the presence of the vacuole can be divided into those which are related merely to the increased volume of the protoplast, independent of the nature of the vacuolar contents, and those ...
openaire +2 more sources
The Toxoplasma gondii active serine hydrolase 4 regulates parasite division and intravacuolar parasite architecture [PDF]
Hydrolase are enzymes that regulate diverse biological processes, including posttranslational protein modifications. Recent work identified four active serine hydrolases (ASHs) in Toxoplasma gondii as candidate depalmitoylases. However, only TgPPT1 (ASH1)
Amara, Neri+7 more
core +2 more sources
ABC transporters linked to multiple herbicide resistance in blackgrass (Alopecurus myosuroides)
Enhanced detoxification is a prominent mechanism protecting plants from toxic xenobiotics and endows resistance to diverse herbicide chemistries in grass weeds such as blackgrass (Alopecurus myosuroides).
Alina Goldberg-Cavalleri+3 more
doaj +1 more source
Quantitation of vacuolar sugar transporter abundance changes using QconCAT synthtetic peptides
Measurements of protein abundance changes are important for biological conclusions on protein-related processes such as activity or complex formation. Proteomic analyses in general are almost routine tasks in many laboratories.
Heidi ePertl-Obermeyer+4 more
doaj +1 more source
The Lack of SNARE Protein Homolog Syn8 Influences Biofilm Formation of Candida glabrata
Biofilm formation of Candida species is considered to be a pathogenic factor of host infection. Since biofilm formation of Candida glabrata has not been as well studied as that of Candida albicans, we performed genetic screening of C. glabrata, and three
Xinyue Chen+4 more
doaj +1 more source