Results 61 to 70 of about 441,117 (305)

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern

open access: yesCells, 2022
Background: Human sperm chromatin condensation is a sum of epigenetic events that allows for the near-complete replacement of histones with protamines.
Marion Bendayan   +6 more
doaj   +1 more source

Adjustment of Host Cells for Accommodation of Symbiotic Bacteria: Vacuole Defunctionalization, HOPS Suppression, and TIP1g Retargeting in Medicago[C][W][OPEN]

open access: yesThe Plant Cell, 2014
The accommodation of thousands of nitrogen-fixing rhizobia in legume root nodules requires changes in functionality of the vacuoles of infected cells. Suppression of HOPS tethering complex genes and tonoplast aquaporin retargeting to symbiosomes is part ...
A. Gavrin   +6 more
semanticscholar   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Delivering of Proteins to the Plant Vacuole—An Update

open access: yesInternational Journal of Molecular Sciences, 2014
Trafficking of soluble cargo to the vacuole is far from being a closed issue as it can occur by different routes and involve different intermediates.
C. Pereira, S. Pereira, J. Pissarra
semanticscholar   +1 more source

Performance Characteristics of Anti‐Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

open access: yesArthritis Care &Research, Accepted Article.
Background Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti‐collagen II (anti‐Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick   +6 more
wiley   +1 more source

Francisella novicida-Containing Vacuole within Dictyostelium discoideum: Isolation and Proteomic Characterization

open access: yesMicroorganisms
Francisella is a highly infectious gram-negative bacterium that causes tularemia in humans and animals. It can survive and multiply in a variety of cells, including macrophages, dendritic cells, amoebae, and arthropod-derived cells.
Valentina Marecic   +10 more
doaj   +1 more source

Some Reflections on Intracytoplasmic Morphologically Selected Sperm Injection [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2014
Although intracytoplasmic sperm injection (ICSI) allows proper fertilization in most cases of male sub fertility, it is one of the most unphysiological techniques in assisted reproductive technologies (ART). Thus, over the last decade, researchers have
Thomas Ebner   +3 more
doaj  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Lipid synthesis and membrane contact sites: a crossroads for cellular physiology

open access: yesJournal of Lipid Research, 2016
Membrane contact sites (MCSs) are regions of close apposition between different organelles that contribute to the functional integration of compartmentalized cellular processes.
J.Pedro Fernández-Murray   +1 more
doaj   +1 more source

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