Results 121 to 130 of about 344,975 (368)

An Estimate of Attributable Cases of Alzheimer Disease and Vascular Dementia due to Modifiable Risk Factors: The Impact of Primary Prevention in Europe and in Italy

Dementia and Geriatric Cognitive Disorders Extra, 2018
Background: Up to 53.7% of all cases of dementia are assumed to be due to Alzheimer disease (AD), while 15.8% are considered to be due to vascular dementia (VaD).
Flavia Mayer, Alessandra Di Pucchio, Eleonora Lacorte, Ilaria Bacigalupo, Fabrizio Marzolini, Gianluigi Ferrante, Valentina Minardi, Maria Masocco, Marco Canevelli, Teresa Di Fiandra, Nicola Vanacore   +10 more
doaj   +1 more source

Clinical effects of combination therapy with continuous renal replacement therapy and continuous intravenous sodium infusion therapy

Therapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This single‐center retrospective study investigated the clinical effects of combination therapy involving continuous renal replacement therapy (CRRT) and continuous intravenous sodium infusion therapy (cIVNa) in critically ill patients with prerenal acute kidney injury (AKI) who were expected to experience insufficient plasma ...
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +5 more
wiley   +1 more source

Clinical Experience With the MEDOS HIA-VAD System in Infants and Children: A Preliminary Report [PDF]

, 1997
Wolfgang Konertz, Holger Hotz, Katja Schneider, Mathias Redlin, H. Reul   +4 more
openalex   +1 more source

Causal Analysis Between Gut Microbes, Aging Indicator, and Age‐Related Disease, Involving the Discovery and Validation of Biomarkers

Aging Cell, EarlyView.
A comprehensive causal effect analysis was used to illustrate the associations between gut microbiota, aging indicators, and age‐related diseases. This study provides evidence that supports the association between the gut microbiota and aging and highlights the potential of genetic correlation and causal relationship analysis in biomarker discovery ...
Chunrong Lu, Xiaojun Wang, Xiaochun Chen, Tao Qin, Pengpeng Ye, Jianqun Liu, Shuai Wang, Weifei Luo   +7 more
wiley   +1 more source

Vascular dementia has the highest hospitalisation rate in China: a nationwide hospital information system study

Stroke and Vascular Neurology
Background Although vascular dementia (VaD) is not uncommon in the hospital, most studies on VaD are community based. This study on VaD is the first to use a national hospital information system (HIS) in China.Methods This study was a hospital population-
Yongjun Wang, Yue Wang, Qi Zhou, Jiong Shi, Shiping Li   +4 more
doaj   +1 more source

Cathepsin B Regulates Ovarian Reserve Quality and Quantity via Mitophagy by Modulating IGF1R Turnover

Aging Cell, EarlyView.
Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty, Anjali Kumari, Lava Kumar. S, Ajith Kumar, Pravin Birajdar, Rohit Beniwal, Mohd Athar, Kiran Kumar. P, H.B.D.Prasada Rao   +8 more
wiley   +1 more source

Treatment of mantle-cell lymphomas with the VAD +/− chiorambucil regimen with or without subsequent high-dose therapy and peripheral blood stem-cell transplantation [PDF]

, 1997
Rémy Gressin, Éric Legouffe, Dominique Leroux, Marie‐Christine Jacob, P Świercz, Michel Péoc’h, V. Capdevilla, Jean François Rossi, A. Thyss, J J Sotto   +9 more
openalex   +1 more source

TFEB Orchestrates Stress Recovery and Paves the Way for Senescence Induction in Human Dermal Fibroblasts

Aging Cell, EarlyView.
TFEB dynamics during oxidative stress‐induced premature senescence. The tBHP treatment undermines GSH‐dependent antioxidant mechanisms, leading to increased ROS production and lysosomal damage. In the stress phase, we observed the concomitant inhibition of Akt along with activation of AMPK, together leading to mTOR inhibition and subsequent ...
Lena Guerrero‐Navarro, Pablo Monfort‐Lanzas, Vinzenz Krichbaumer, Mariana E. G. De Araújo, Jlenia Monfregola, Lukas A. Huber, Andrea Ballabio, Pidder Jansen‐Dürr, Maria Cavinato   +8 more
wiley   +1 more source

Durable mechanical circulatory support in paediatric heart failure: The experience at Great Ormond Street Hospital

Cirugía Cardiovascular, 2019
Durable ventricular assist devices (VAD), despite being a standard therapy for adults in end-stage heart failure, are not so extended among the paediatric population for some reasons.
Ana Redondo, Ben Davies, Rebecca Jones, Maura O’Callaghan, Martin Kostolny   +4 more
doaj  

Comparison of 2nd generation LiDAR wind measurement technique with CFD numerical modelling [PDF]

, 2012
With the rapid increase in both on and offshore wind turbine deployment there is a requirement for a better understanding of the flow field in which such devices are deployed.
Butler, Jonathan, Quail, Francis
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