Results 121 to 130 of about 267,305 (204)
Inhibition of Apoptosis by Z-VAD-fmk in SMN-depleted S2 Cells [PDF]
Ilangovan Raju+3 more
openalex +1 more source
PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang+10 more
wiley +1 more source
Editorial: Hemostasis in ECMO and VAD
M. Patricia Massicotte+2 more
openaire +4 more sources
Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal Toxicity
Extracellular SARS‐CoV2 Spike‐S1 protein via NRP1 internalizes in the cytosol of SH‐SY5Y cells. Once inside, it upregulates the epigenetic eraser HDAC4, which binds transcriptional factor CREB, causes RIPK1 up‐regulation, and therefore necroptotic cell death.
Luca Sanguigno+8 more
wiley +1 more source
How to Run an Outpatient VAD Program: Overview
William L. Holman+4 more
openalex +1 more source