Results 51 to 60 of about 344,975 (368)

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Recomendaciones para el manejo de la Vía Aérea Difícil. 2ª Parte. La Vía Aérea Anticipada

Revista Electrónica de AnestesiaR, 1970
La adopción de un plan cuando se sospecha una Vía Aérea Difícil (VAD) es fundamental para evitar la morbi-mortalidad, y cuando se planifica el abordaje de la VAD lo primero que tenemos que tener en cuenta es si podremos oxigenar y ventilar al paciente, y
Eugenio Martínez Hurtado, Miriam Sánchez Merchante   +1 more
doaj   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Predictores de Intubación Difícil en la consulta perioperatoria de Otorrinolaringología. Revisión 2015

Revista Electrónica de AnestesiaR, 2015
Resulta fundamental la identificación con suficiente antelación de pacientes con probable Vía Aérea Difícil (VAD) para asegurar un manejo adecuado de tipo multidisciplinar. Para ello, deberemos realizar una exhaustiva historia clínica y anamnesis.
Nerea Igartua Larrañaga
doaj   +1 more source

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

Advanced Science, EarlyView.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu, Lingxiao Guo, Yuying Cheng, Jingjie Gao, Hanling Pan, Jiayi Zhu, Danting Li, Liqing Jiao, Caiyun Fu   +8 more
wiley   +1 more source

Videolaringoscopios Pentax-AWS y Glidescope como alternativa al laringoscopio Macintosh en la dificultad de intubación prevista

Revista Electrónica de AnestesiaR, 1970
La dificultad y la imposibilidad para la intubación orotraqueal (IOT) suponen la principal causa de morbilidad y mortalidad de causa anestésica. Los videolaringoscopios (VL) se han desarrollado para reducir la dificultad de intubación laríngea ...
Belén Cobo García
doaj   +1 more source

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen, Ji‐Jun Shan, Mo Chen, Zong Wu, Yi‐Ming Zhao, Hong‐Xu Zhu, Xin Jin, Yi‐Xiu Wang, Yi‐Bin Wu, Zhen Xiang, Zhi‐Wen Ding, Zhen‐Hai Lin, Long‐Rong Wang, Lu Wang   +13 more
wiley   +1 more source

Manejo de la vía aérea en un paciente con secuencia de Pierre Robin para la cirugía de distracción osteogénica mandibular

Revista Electrónica de AnestesiaR, 2015
El síndrome o secuencia de Pierre Robin (SPR) es una rara afección genética con una incidencia de 1 por cada 8.500 recién nacidos, descrita en 1923 por Robin. Se caracteriza por la triada clásica de glosoptosis, obstrucción de la vía aérea y alteraciones
Rosana Guerrero Domínguez, Daniel López-Herrera Rodríguez, Jesús Acosta Martínez   +2 more
doaj   +1 more source

Replenishment of vitamin A for 7 days partially restored hepatic gene expressions altered by its deficiency in rats

Frontiers in Nutrition, 2022
We investigated the effects of vitamin A (VA) status on metabolism of Zucker rats with different genders and genotypes, and of short-term refeeding of a VA sufficient (VAS) diet on VA deficient (VAD) animals.
Yan Zhang, Kui Tian, Guoxun Chen
doaj   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source