Results 71 to 80 of about 31,199 (169)

Whole‐body hot water immersion effect on cerebral haemodynamics and subsequent cerebrovascular reactivity to carbon dioxide

Experimental Physiology, EarlyView.
Abstract To test the hypothesis that hot water immersion (HWI) improves cerebrovascular function via shear‐mediated mechanisms, this study determined cerebrovascular reactivity to carbon dioxide (CVRCO2${\mathrm{CV}}{{\mathrm{R}}_{{\mathrm{C}}{{\mathrm{O}}_2}}}$) before and after 60 min of 39°C HWI and a 21°C air control (CON) in 15 healthy ...
Samuel F. Leaney, Ester Tommasini, Guto W. Hughes, Alison M. Shepherd, Nyah D. Kingdon, Justin S. Lawley, Geoff B. Coombs, Jonathan P. Moore, Samuel J. Oliver   +8 more
wiley   +1 more source

Role of inflammatory cytokines and the gut microbiome in vascular dementia: insights from Mendelian randomization analysis

Frontiers in Microbiology
BackgroundBoth inflammatory cytokines and the gut microbiome are susceptibility factors for vascular dementia (VaD). The trends in the overall changes in the dynamics of inflammatory cytokines and in the composition of the gut microbiome are influenced ...
Yihan Yang, Ting Rao, Ting Rao, Sheng Wei, Jing Cheng, Ying Zhan, Teng Lin, Jincheng Chen, Jincheng Chen, Xiaoling Zhong, Yijing Jiang, Shanli Yang   +11 more
doaj   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Predicting the Epidemiological Effects in the United Kingdom of Moving from PCV13 to PCV15 in the Routine Pediatric 1 + 1 Vaccination Schedule

Vaccines
Background/Objectives: Pneumococcal conjugate vaccines (PCVs) were first introduced in the pediatric UK National Immunization Programme (NIP) in 2006 and subsequently led to a significant decline in invasive pneumococcal disease (IPD).
Rachel J. Oidtman, Natalie Banniettis, Jessica Weaver, Ian R. Matthews, Dionysios Ntais, Giulio Meleleo, Tufail M. Malik, John C. Lang, Oluwaseun Sharomi   +8 more
doaj   +1 more source

Revisiting Amplitude of Low‐Frequency Fluctuations (ALFF) in Resting‐State fMRI: Clarifications and Improvements

Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.
We provide a mathematical clarification of ALFF and fALFF by introducing two variants: the arithmetic mean‐defined and the quadratic mean‐defined to clarify the inconsistencies in the definition and implementation of (f)ALFF. ABSTRACT The amplitude of low‐frequency fluctuations (ALFF) and its related measure, fractional ALFF (fALFF), are widely used ...
Lejian Huang, Rami Jabakhanji, Andrew D. Vigotsky, Paulo Branco, Marwan N. Baliki, A. Vania Apkarian   +5 more
wiley   +1 more source

Vascular dementia has the highest hospitalisation rate in China: a nationwide hospital information system study

Stroke and Vascular Neurology
Background Although vascular dementia (VaD) is not uncommon in the hospital, most studies on VaD are community based. This study on VaD is the first to use a national hospital information system (HIS) in China.Methods This study was a hospital population-
Yongjun Wang, Yue Wang, Qi Zhou, Jiong Shi, Shiping Li   +4 more
doaj   +1 more source

What Goes First? Effects of Starvation on the Body Condition of a Neotropical Dung Beetle

Entomologia Experimentalis et Applicata, Volume 174, Issue 4, Page 321-328, April 2026.
We investigated how prolonged starvation affects key physiological traits in the dung beetle Dichotomius bos. Prolonged starvation leads to significant reductions in body dry mass and fat reserves, while muscle mass remains unchanged. These findings indicate that dung beetles prioritize the maintenance of locomotor muscles while mobilizing stored ...
Leonardo Vilas‐Bôas M. P. de Cerqueira, Renato Portela Salomão, Damián Villaseñor‐Amador, Andressa Fraga Cotta, Pedro Lucas Moreira de Oliveira, César Murilo de Albuquerque Correa   +5 more
wiley   +1 more source

The Association Between Caregiver Psychosocial Factors and Depressive Symptoms in People With Dementia: A Systematic Review and Meta‐Analysis

Journal of Advanced Nursing, Volume 82, Issue 4, Page 3906-3942, April 2026.
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning, Shanshan Wang, Yudi Xu, Daphne Cheung   +3 more
wiley   +1 more source

Sjuttonhundratalets vetenskap – vad hände och vad händer?

Lychnos, 2008
This essay documents the historiography of 18th century Swedish science and its main organizers Johan Nordström and his successor as professor of history of science and ideas at Uppsala University Sten Lindroth, active within this discipline until 1979.
Gunnar Broberg
doaj  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, Volume 20, Issue 3, Page 588-610, March 2026.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source