Results 71 to 80 of about 363,273 (339)

An Affect-Rich Neural Conversational Model with Biased Attention and Weighted Cross-Entropy Loss

, 2018
Affect conveys important implicit information in human communication. Having the capability to correctly express affect during human-machine conversations is one of the major milestones in artificial intelligence.
Miao, Chunyan, Wang, Di, Zhong, Peixiang
core   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Manejo de la vía aérea en un paciente con secuencia de Pierre Robin para la cirugía de distracción osteogénica mandibular

Revista Electrónica de AnestesiaR, 2015
El síndrome o secuencia de Pierre Robin (SPR) es una rara afección genética con una incidencia de 1 por cada 8.500 recién nacidos, descrita en 1923 por Robin. Se caracteriza por la triada clásica de glosoptosis, obstrucción de la vía aérea y alteraciones
Rosana Guerrero Domínguez, Daniel López-Herrera Rodríguez, Jesús Acosta Martínez   +2 more
doaj   +1 more source

Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study. [PDF]

, 2010
INTRODUCTION: Evidence from clinical samples and geographically limited population studies suggests that vascular health, diabetes and apolipoprotein epsilon4 (APOE) are associated with dementia. METHODS: A population-based sample of 856 individuals aged
Fisher, Gwenith G, Kabeto, Mohammed U, Lang, Iain A, Langa, Kenneth M, Llewellyn, David J, Matthews, Fiona E, Morgenstern, Lewis B, Plassman, Brenda L, Rogers, Mary A   +8 more
core   +5 more sources

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

¿Vía Aérea Difícil y Cirugía Ambulatoria…?

Revista Electrónica de AnestesiaR, 2013
Esta revisión tiene como objetivos revisar 2 aspectos clave del manejo de la Vía Aérea Difícil (VAD) en cirugía ambulatoria. El proceso de selección de los pacientes con VAD conocida y el equipamiento que necesita el carro de VA para el manejo de una VAD
Briseida V Arrázola Cabrera, Jolanta B Tomaszewska, Andrzej P Walczak, Marisa Mariscal Flores   +3 more
doaj   +1 more source

An advanced universal circulatory assist device for left and right ventricular support: First report of an acute in vivo implantCentral MessagePerspective

JTCVS Open, 2020
Background: The Advanced ventricular assist device (Advanced VAD) is designed as a universal pump intended to prevent backflow in the event of pump stoppage, to maintain physiological pulse pressure, and to be used as both a left and right VAD.
Takuma Miyamoto, MD, PhD, Yuichiro Kado, MD, PhD, David J. Horvath, MSME, Barry D. Kuban, BS, Shiva Sale, MD, Kiyotaka Fukamachi, MD, PhD, Jamshid H. Karimov, MD, PhD   +6 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Preparación y Educación en el manejo de la Vía Aérea. Revisión 2015

Revista Electrónica de AnestesiaR, 1970
El propósito de la Educación Médica en cualquier campo, prepara al profesional para la adquisición de conocimientos, habilidades y profesionalidad necesaria para aportar un cuidado correcto al paciente.
Marisa Mariscal Flores, Eugenio Martínez Hurtado   +1 more
doaj   +1 more source

Replenishment of vitamin A for 7 days partially restored hepatic gene expressions altered by its deficiency in rats

Frontiers in Nutrition, 2022
We investigated the effects of vitamin A (VA) status on metabolism of Zucker rats with different genders and genotypes, and of short-term refeeding of a VA sufficient (VAS) diet on VA deficient (VAD) animals.
Yan Zhang, Kui Tian, Guoxun Chen
doaj   +1 more source