Results 121 to 130 of about 137,793 (295)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Molecular bases of insect odorant receptor function: specificity and evolution

open access: yesBiological Reviews, EarlyView.
ABSTRACT Insect odorant receptors (ORs) are a class of chemoreceptors that insects use to detect volatile cues in their environment. In recent years, major advances in the field of structural biology have made it possible to obtain the first structures of insect ORs.
Zibo Li   +5 more
wiley   +1 more source

Photoinduced Boron‐Catalyzed Direct α‐Aminoxylation of Carboxylic Acids

open access: yesChemistryEurope, EarlyView.
A boron‐catalyzed α‐aminoxylation of carboxylic acids enables rapid access to sterically congested α‐(aminoxy)carboxylic acids. Photoexcited diboron enediolates transfer energy to O‐sulfonylhydroxylamines, triggering SO bond cleavage to generate N‐oxyl radicals.
Tsubasa Oyama   +5 more
wiley   +1 more source

Use of metabolic profile in short-term studies for estimating optimum dietary isoleucine, leucine, and valine for pigs

open access: green, 2017
Jan Værum Nørgaard   +5 more
openalex   +2 more sources

The Wuhan Pneumonia Outbreak: High Isoleucine and High Valine Plus Glycine Contents Are Features of the Proteins of 2019-nCoV Virus

open access: green, 2020
Sirui Yan   +6 more
openalex   +1 more source

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

open access: yesChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn   +6 more
wiley   +1 more source

Enantioselective Synthesis of Sulfinamidines via Asymmetric Rhodium–Catalyzed Imidation of Sulfenamides

open access: yesChemistryEurope, EarlyView.
In this work, a catalytic enantioselective imidation approach is presented for the preparation of enantioenriched sulfinamidines from sulfenamides, employing a chiral dirhodium(II) tetracarboxylate catalyst. This method enables the imidation of N,N‐bisalkyl sulfenamides in yields of up to 98% and enantiomeric ratios up to 98:2, with a catalyst loading ...
Michael Andresini   +7 more
wiley   +1 more source

Solvent‐Driven Pore Engineering in Coffee‐Derived Activated Hydrochar: Implications for Post‐Combustion CO2 Capture

open access: yesCarbon Energy, EarlyView.
Solvent washing of coffee‐ground hydrochars produces activated carbons with tunable pore sizes while maintaining surface area. Removing non‐polar contaminants enhances microporosity, increasing CO2 uptake by 40%. Moderate pore sizes (9–12 Å) yield optimal CO2:N2 selectivity, whereas smaller pores reduce selectivity due to stronger interactions between ...
Muhammad Irfan Maulana Kusdhany   +4 more
wiley   +1 more source

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