Results 131 to 140 of about 279,014 (342)

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Structural characterization of the D290V mutation site in hnRNPA2 low-complexity-domain polymers. [PDF]

, 2018
Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2
Kato, Masato, McKnight, Steven L, Murray, Dylan T, Tycko, Robert, Xiang, Siheng, Zhou, Xiaoming   +5 more
core  

Joseph Alphonse Valin [PDF]

Ontario History, 2017
After Confederation, the provinces administered justice but the dominion government appointed judges. In 1894 Ontario’s Mowat government passed legislation to create Nipissing judicial district. It was then up to the Dominion government to appoint a judge. By early 1895, the Bowell administration issued an order-in-council and the new judge was waiting
openaire   +1 more source

Evaluation of in situ valine production by Bacillus subtilis in young pigs

Animal, 2016
Mutants of Bacillus subtilis can be developed to overproduce Val in vitro. It was hypothesized that addition of Bacillus subtilis mutants to pig diets can be a strategy to supply the animal with Val.
J.V. Nørgaard, N. Canibe, E.A. Soumeh, B.B. Jensen, B. Nielsen, P. Derkx, M.D. Cantor, K. Blaabjerg, H.D. Poulsen   +8 more
doaj   +1 more source

Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging

PLoS Genetics, 2014
Dietary restriction extends longevity in organisms ranging from bacteria to mice and protects primates from a variety of diseases, but the contribution of each dietary component to aging is poorly understood. Here we demonstrate that glucose and specific
M. Mirisola, G. Taormina, P. Fabrizio, Min Wei, Jia Hu, V. Longo   +5 more
semanticscholar   +1 more source

Branched-chain amino acid supplementation and voluntary running have distinct effects on the serum metabolome of rats with high or low intrinsic aerobic capacity

Frontiers in Nutrition
IntroductionA growing body of literature associates branched-chain amino acid (BCAA) catabolism to increased fatty acid oxidation and better metabolic health. Hence, BCAA-rich diets may improve body composition and muscle protein synthesis.
Sira Karvinen, Tia-Marje K. Korhonen, Ronja Kiviö, Sanna Lensu, Sanna Lensu, Bharat Gajera, Steven L. Britton, Steven L. Britton, Lauren G. Koch, Anni I. Nieminen, Heikki Kainulainen   +10 more
doaj   +1 more source

Modulating Taste Perception in Newly Weaned Piglets: The Role of Palatability Additives in Enhancing Feed Intake and Performance

Animal Research and One Health, EarlyView.
Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht, Gabriela Altenhofen, Daiane Carvalho, Michele Fangmeier   +3 more
wiley   +1 more source

Applied Research Note: Influence of dietary fat and crystalline amino acid inclusion on broiler diet formulation and subsequent pellet quality

Journal of Applied Poultry Research
SUMMARY: A total of 3 broiler diets were pelleted to determine the effects of diet formulation on pellet quality. Dietary treatments consisted of corn and soybean meal-based control, the control with crystalline valine (Val), and the control with ...
K.M. Dunmire, J. Lee, K. Haydon, C.R. Stark, C.B. Paulk   +4 more
doaj   +1 more source

Biosynthesis of food constituents: Amino acids: 2. The alanine-valine-leucine, serine-cysteine-glycine, and aromatic and heterocyclic amino acids groups - a review

Czech Journal of Food Sciences, 2006
This review article gives a survey of principal pathways that lead to the biosynthesis of the proteinogenic amino acids of the alanine-valine-leucine group starting with pyruvic acid from the glycolytic pathway and serine-cysteine-glycine group starting ...
Jan Velíšek, Karel Cejpek
doaj   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source