Results 121 to 130 of about 138,081 (263)
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat +14 more
wiley +1 more source
Second‐trimester multimetabolite panel for early preeclampsia rule‐out
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins +7 more
wiley +1 more source
Amino acids: Missing link in preeclampsia pathogenesis? [PDF]
Gezer IS +7 more
europepmc +1 more source
Advances in sequencing and mass spectrometry have propelled life sciences into the multi‐omics era. Metabolomics and microbiomics are widely applied across various research fields, yet massive data analysis faces challenges like limited tool functionality and high technical barriers.
Jianhua Zhao +16 more
wiley +1 more source
HLA-DR risk variants in rheumatoid arthritis: what we know and still do not know. [PDF]
Yap CF, Viatte S.
europepmc +1 more source
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda +8 more
wiley +1 more source
Determination of the structure and dynamics of linear polypeptide gramicidin A at atomic-scale resolution. [PDF]
Laxmi Pradhan B +5 more
europepmc +1 more source
Maternal and infant gut microbiome
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang +25 more
wiley +1 more source
Effects of varying levels of valine supplementation on meat metabolism and rumen microorganisms in Tibetan sheep. [PDF]
Wang F +8 more
europepmc +1 more source

