Results 151 to 160 of about 225,375 (330)

Isoleucine and Valine Metabolism in Escherichia coli

open access: hybrid, 1958
H. E. Umbarger, Barbara Brown
openalex   +1 more source

Investigating the Site‐Specific Impact of Fluorine Substitution on Aromatic Interactions in a Tryptophan Zipper Peptide

open access: yesChemistry – A European Journal, EarlyView.
Constitutional isomers of fluoro‐tryptophan alter the stability of the β‐hairpin peptide Trpzip2 by tuning key CH/π and NH/π interactions. Abstract The stability of pairwise tryptophan (Trp) edge‐to‐face aromatic interactions has been exploited in the design of small tryptophan zipper (Trpzip) peptides.
David Reiter   +6 more
wiley   +1 more source

The Ascent of Supramolecular Polymers and Gels in Asymmetric Catalysis

open access: yesChemistry – A European Journal, EarlyView.
SPs and gels emerged as modular platforms for asymmetric catalysis. This review ranks literature reports according to the achiral or chiral nature of the monomers bearing the catalytic site. New paradigms showcased by this approach are particularly highlighted, such as catalysts operating with a low amount of chiral inducers, or with no chiral inducer,
Ran Chen   +2 more
wiley   +1 more source

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

open access: yesChemMedChem, Accepted Article.
Continuing our research aimed at discovering new BAG3 modulators as attractive anticancer drug candidates, we performed a screening campaign on an in‐house library, including compounds featuring a large variety of scaffolds. The obtained results induced us to focus on the triazole moiety and, following a stepwise structural refinement of the scaffold ...
Dafne Ruggiero   +10 more
wiley   +1 more source

Vibrational Partition Functions from Bond Order and Populations Relationships

open access: yesChemPhysChem, EarlyView.
A new computational model is presented that predicts vibrational partition functions using bond orders and populations relationships (QBOP). This model demonstrates that thermochemical energy contributions can be reasonably approximated based on well‐conditioned orbital populations without the need for a costly Hessian calculation.
Barbaro Zulueta, John A. Keith
wiley   +1 more source

Bombyx Mori Silk Fibroin as a Sustainable Organocatalyst for Diastereoselective Michael Additions

open access: yesChemSusChem, EarlyView.
Silk fibroin, natural biopolymer, has been successfully used as green catalyst for Michael addition reactions under mild conditions. Its pseudoenzymatic pocket enables enzyme‐like catalytic behavior, driving stereoselectivity, and highlighting a sustainable, nature‐inspired catalytic approach.
Carola Ricciardelli   +8 more
wiley   +1 more source

Microfluidic‐Assisted Evolution of a Robust NAD+‐Dependent Enzyme with Improved Isobutanol Tolerance at Elevated Temperatures

open access: yesChemSusChem, EarlyView.
Utilizing the power of the absorbance‐activated droplet sorter, a key enzyme for a cell‐free multienzymatic cascade for sustainable isobutanol biosynthesis is optimized for improved thermostability and isobutanol tolerance required for efficient cascade performance.
Mariko Teshima   +6 more
wiley   +1 more source

Screening and Quantification of the Synthetic Cannabinoid Receptor Agonist 5F‐MDMB‐PINACA From Seized Prison Paper Using Ultraperformance Liquid Chromatography–Mass Spectrometry Approaches

open access: yesDrug Testing and Analysis, EarlyView.
Synthetic cannabinoid receptor agonists are being infused on paper and illicitly introduced into prisons through mail correspondence. An approach to quantify and map the synthetic cannabinoid 5F‐ADB on a seized paper sample from a UK prison was determined using ultraperformance liquid chromatography–quadrupole Dalton–mass spectrometry.
Giorgia Vaccaro   +4 more
wiley   +1 more source

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