Fluorination as a Molecular Design Parameter for Programming Peptide Nanocarriers
Small, EarlyView.Controlled side‐chain fluorination programs the SA, morphology, and biological performance of amphiphilic fluoropeptide–RGD nanocarriers. A narrow fluorination window yields compact non‐amyloid fibrils with high loading capacity, pH‐triggered release, receptor‐specific uptake, low cytotoxicity, and enzymatic degradability.
Maurizio Iannuzzi +10 more
wiley +1 more source
High-Sensitivity Terahertz Sensors for Sample Detection. [PDF]
Sensors (Basel)Wei D.
europepmc +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir +4 more
wiley +1 more source
Causal role of genetically predicted impairment of branched-chain amino acid catabolism on insulin secretion and insulin resistance in type 2 diabetes. [PDF]
Diabetes Obes MetabZhou X, Lu J, Wang Z, Cheng KK, Li GH.
europepmc +1 more source
THE BIOSYNTHESIS OF VALINE BY SACCHAROMYCES CEREVISIAE
Journal of Biological Chemistry, 1954 openaire +2 more sources
Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy
VIEW, EarlyView.This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley +1 more source
Potential Treatment for ADHD Based on Recovery from Tryptophan-Induced Central Fatigue by Powerful Competitive Inhibition of L-System Amino Acid Transporter. [PDF]
Int J Tryptophan ResYamamoto T, Koleda-Yamamoto B.
europepmc +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Characterization, evolutionary analysis, and expression profiling of the <i>VrPYL</i> gene family in mung bean in response to abiotic stress. [PDF]
PeerJYin L, Xiao Y, Liao J, Zhang D, Chen X.
europepmc +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing +9 more
wiley +1 more source