Results 231 to 240 of about 137,793 (295)

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

open access: yesSmall, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi   +11 more
wiley   +1 more source

Kinetically Controlled Self‐Assembly of a Lipophilic Fluorophore with Phenylalanine‐Based Diamides in Artificial Lipid Droplets

open access: yesSmall, EarlyView.
Fibrous aggregates in triolein are constructed from a lipophilic donor–acceptor fluorophore bearing two phenylalanine‐based diamide units. Spectroscopic analyses and fluorescence imaging revealed a kinetically trapped state persisting for hours, enabling seeded modulation of aggregate size in artificial lipid droplets encapsulating triolein within a ...
Miku Naruse   +6 more
wiley   +1 more source

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos   +3 more
wiley   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese   +13 more
wiley   +1 more source

Valine-Niclosamide for Treatment of Androgen Receptor Splice Variant-Positive Hepatocellular Carcinoma. [PDF]

open access: yesCancers (Basel)
Hoelzen EJ   +15 more
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng   +3 more
wiley   +1 more source

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