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BAY 43-9006 inhibition of oncogenic RET proteins: activity on gate-keeper mutants
Anaganti, Suresh
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Valine kinetics at graded valine intakes in young men
American Journal of Clinical Nutrition, 1986Twelve young men, six subjects in each group studied in two phases, participated in an experiment to explore the relationships between valine intake, plasma valine concentrations, and valine kinetics, using 1-[13C]valine as a tracer. Below a valine intake of about 20 mg.kg-1.day-1 plasma valine concentrations reached a low and relatively constant level.
D M Bier +2 more
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Influence of valine flooding on channeling of valine into tissue pools and on protein synthesis
Rates of valine incorporation into protein were measured under control and valine-"flooding" conditions and included correction for the degree of recycling of unlabeled valine derived from the steady-state breakdown of tissue protein into the precursor pool (tRNA bound).
C B, Smith, Y, Sun
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Neurochemical Research, 2009
The three essential amino acids, valine, leucine and isoleucine, constitute the group of branched-chain amino acids (BCAAs). BCAAs are rapidly taken up into the brain parenchyma, where they serve several distinct functions including that as fuel material in brain energy metabolism.
Radovan, Murín +3 more
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The three essential amino acids, valine, leucine and isoleucine, constitute the group of branched-chain amino acids (BCAAs). BCAAs are rapidly taken up into the brain parenchyma, where they serve several distinct functions including that as fuel material in brain energy metabolism.
Radovan, Murín +3 more
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Interorgan metabolism of valine
Amino Acids, 1991Oxidation of branched-chain amino acids, leucine, isoleucine and valine, is thought to occur primarily in muscle. Theoretically, however, it is possible for valine carbon to be converted to glucose, a process which only occurs in liver and kidney. We provide evidence that valine is oxidixed toβ-hydroxyisobutyrate in muscle, and that this intermediate ...
M E, Brosnan, J, Letto
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VALINE-ISOLEUCINE METABOLISM IN ACETOBACTER SUBOXYDANS AND THE INHIBITION OF GROWTH BY VALINE
Journal of Bacteriology, 1964Kerwar, Suresh S. (Oregon State University, Corvallis), Vernon, H. Cheldelin, and L. W. Parks . Valine-isoleucine metabolism in Acetobacter suboxydans and the inhibition of growth by valine. J. Bacteriol. 88: 179–186.
S S, KERWAR, V H, CHELDELIN, L W, PARKS
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Regulation of Isoleucine and Valine Biosynthesis
1978Publisher Summary This chapter discusses the regulation of isoleucine and valine biosynthesis. Isoleucine and valine biosynthesis is a model system for the study of mechanisms by which the cell coordinates different parts of its total metabolism. Threonine deaminase is the first enzyme in isoleucine biosynthesis.
Iaccarino M. +3 more
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Inhibition of valine utilization by cyclobutaneglycine
Archives of Biochemistry and Biophysics, 1977Abstract dl -Cyclobutaneglycine formed by basic hydrolysis of 5-cyclobutylhydantoin prevents the growth of Escherichia coil W in an inorganic salts-glucose medium. This inhibitory effect of the amino acid analog is reversed in a competitive manner over a wide range of concentrations specifically by l -valine.
T H, Porter, S C, Smith, W, Shive
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Study of the Coordinated System Cd(II)-Valine-Valinate Ion
Collection of Czechoslovak Chemical Communications, 1992The polarographic method has been applied to the study of the coordinated systems Cd(II)-neutral valine and Cd(II)-valinate ion in aqueous medium and I = 1.0 mol l-1 (NaClO4). The stability constants of the complexes were determined as: [Cd(HV)]2+ (β10 = 7 ± 0.5), [Cd(HV)2]2+ (β20 = 24 ± 4), [Cd(HV)3]2+ [β30 = (1.5 ± 0.32) . 102], [Cd(V-)]+ [β01 = (4.1
Jesús César Rodríguez Placeres +3 more
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