Results 61 to 70 of about 279,014 (342)

Phylogenomic study of Burkholderia glathei-like organisms, proposal of 13 novel Burkholderia species and emended descriptions of Burkholderia sordidicola, Burkholderia zhejiangensis, and Burkholderia grimmiae [PDF]

, 2016
Partial gyrB gene sequence analysis of 17 isolates from human and environmental sources revealed 13 clusters of strains and identified them as Burkholderia glathei Glade (BGC) bacteria.
Cooper, Vaughn S, De Brandt, Evie, Meier-Kolthoff, Jan P, Peeters, Charlotte, Vandamme, Peter, Verheyde, Bart   +5 more
core   +3 more sources

Valine increases milk fat synthesis in mammary gland of gilts through stimulating AKT/MTOR/SREBP1 pathway†

Biology of Reproduction, 2019
Lactating mammary glands are among the most active lipogenic organs and provide a large percentage of bioactive lipids and calories for infant growth.
Long Che, Mengmeng Xu, K. Gao, Cui Zhu, Li Wang, Xuefen Yang, Xiaolu Wen, Hao Xiao, Zong-yong Jiang, De Wu   +9 more
semanticscholar   +1 more source

Solid-state conformation of copolymers of ß-benzyl-L-aspartate with L-alanine, L-leucine, L-valine, γ-benzyl-L-glutamate, or ε-carbobenzoxy-L-lysine [PDF]

, 1980
The solid-state conformation of copolymers of ß-benzyl-L-aspartate [L-Asp(OBzl)] with L-leucine (L-Leu), L-alanine (L-Ala), L-valine (L-Val), γ-benzyl-L-glutamate [L-Glu(OBzl)], or ε-carbobenzoxy-L-lysine (Cbz-L-Lys) has been studied by ir spectroscopy ...
Anderson, James M., Bantjes, Adriaan, Feijen, Jan, Sederel, Willem L.   +3 more
core   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Antioxidant Activity of New Aramide Nanoparticles Containing Redox-Active <em>N</em>-phthaloyl Valine Moieties in the Hepatic Cytochrome P₄₅₀ System in Male Rats

Molecules, 2012
We report the synthesis of aramide nanoparticles containing a chiral <em>N</em>-phthaloyl valine moiety and their antioxidant activities on hepatic contents of cytochrome P₄₅₀, amidopyrene <em>N</em> ...
Hammed H. A. M. Hassan, Sabah G. El-Banna, Amel F. Elhusseiny, El-Sayed M. E. Mansour   +3 more
doaj   +1 more source

Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides [PDF]

, 1993
Synthetic peptides of the five alternative NH2-terminal sequences of Shaker when applied to the cytoplasmic side of ShB channels that have an NH2-terminal deletion (ShB delta 6-46) block the channel with potencies correlated with the rate of inactivation
Aldrich, Richard W, Murrell-Lagnado, Ruth D   +1 more
core   +3 more sources

Dissociation of Valine Cluster Cations [PDF]

The Journal of Physical Chemistry A, 2020
Independently of the preparation method, for cluster cations of aliphatic amino acids, the protonated form MnH+ is always the dominant species. This is a surprising fact considering that in the gas phase, they dissociate primarily by the loss of 45 Da, i.e., the loss of the carboxylic group. In the present study, we explore the dissociation dynamics of
Lukas Tiefenthaler, Milan Ončák, Siegfried Kollotzek, Jaroslav Kočišek, Paul Scheier   +4 more
openaire   +3 more sources

Targeting HIBCH to reprogram valine metabolism for the treatment of colorectal cancer

Cell Death and Disease, 2019
Valine catabolism is known to be essential for cancer cells but the detailed mechanism remains unclear. This study is to explore the critical roles of 3-hydroxyisobutyryl-CoA hydrolase (HIBCH) in colorectal cancers (CRC) and to develop a new therapy ...
Yun-long Shan, Yuan Gao, W. Jin, Minmin Fan, Ying Wang, Yanhong Gu, Chenxiao Shan, Lijun Sun, Xin Li, Biao Yu, Qiong Luo, Qiang Xu   +11 more
semanticscholar   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Response of piglets to the valine content in diet in combination with the supply of other branched-chain amino acids

Animal, 2011
The branched-chain amino acids (BCAA) valine (Val) and isoleucine (Ile) are considered to be among the next-limiting amino acids for growth in piglets.
M. Gloaguen, N. Le Floc'h, L. Brossard, R. Barea, Y. Primot, E. Corrent, J. van Milgen   +6 more
doaj   +1 more source