Results 71 to 80 of about 279,014 (342)

Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study [PDF]

, 2017
Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.
Brguljan-Hitij, Jana, Cauwenberghs, Nicholas, Delles, Christian, Knez, Judita, Kuznetsova, Tatiana, Marrachelli, Vannina G., Monleon, Daniel, Nawrot, Tim S., Plusquin, Michelle, Redón, Josep, Staessen, Jan A., Thijs, Lutgarde, Winckelmans, Ellen, Zhang, Zhenyu   +13 more
core   +2 more sources

A High Level of Circulating Valine Is a Biomarker for Type 2 Diabetes and Associated with the Hypoglycemic Effect of Sitagliptin

Mediators of Inflammation, 2019
Background High levels of branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) were associated with an increased risk of hyperglycemia and the onset of diabetes. This study is aimed at assessing circulating valine concentrations in subjects
Xiaoyu Liao, Bingyao Liu, H. Qu, LinLin Zhang, Yongling Lu, Yong Xu, Z. Lyu, Hongting Zheng   +7 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Valine metabolite, 3-hydroxyisobutyrate, promotes lipid metabolism and cell proliferation in porcine mammary gland epithelial cells

Frontiers in Nutrition
Improving mammary gland epithelial cells proliferation through nutrition is an important approach for enhancing sow milk production and piglet growth. An intermediate metabolite of valine, 3-hydroxyisobutyrate (3-HIB), regulates cellular lipid metabolism.
Long Che, Long Che, Long Che, Le Liu, Mengmeng Xu, Zongze Fan, Lizhu Niu, Yujie Chen, Xueyuan Chang, Pan Zhou, Mengyun Li, Hongyu Deng, Wen Chen   +12 more
doaj   +1 more source

Computer quantum chemical modeling of the interaction of calcium phosphate with amino acids

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
In this work, a quantum-chemical modeling of the process of interaction of calcium phosphate with amino acids was carried out. Within the framework of the quantum chemical modeling, the total energy of the molecular complex E, the energy difference ...
A.A. Blinova, A.V. Blinov, M.A. Pirogov, D.G. Maglakelidze, A.A. Yakovenko   +4 more
doaj   +1 more source

Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian [PDF]

, 2009
Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Fuhou Chang, Guang Wang, Jia Ma, Jun QI, Min-jie Wang, Qin Yin, Zhi-Xie Zhang   +6 more
core   +1 more source

Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens

Frontiers in Immunology, 2017
The emergence of multidrug-resistant bacteria presents a severe threat to public health and causes extensive losses in livestock husbandry and aquaculture. Effective strategies to control such infections are in high demand.
Xin-hai Chen, Shi-Rao Liu, Bo Peng, Dan Li, Zhi-xue Cheng, Jia-xin Zhu, Song Zhang, Yu Peng, Hui Li, Tian-tuo Zhang, Xuan-xian Peng   +10 more
semanticscholar   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

Branched-chain amino acids linked to depression in young adults

Frontiers in Neuroscience, 2022
Depression is a heterogeneous mental health problem affecting millions worldwide, but a majority of individuals with depression do not experience relief from initial treatments. Therefore, we need to improve our understanding of the biology of depression.
Alyce M. Whipp, Alyce M. Whipp, Marja Heinonen-Guzejev, Kirsi H. Pietiläinen, Kirsi H. Pietiläinen, Irene van Kamp, Jaakko Kaprio, Jaakko Kaprio   +7 more
doaj   +1 more source

Targeting the muscle for the treatment and prevention of hepatic encephalopathy [PDF]

, 2016
Muscle mass loss or sarcopenia is a principle component of malnutrition which prevails in 65–90% of patients with end-stage liver disease [1]. Intuitively, the roots of malnutrition play a precipitating role in muscle catabolism.
Bémeur, Chantal, Rombouts, Krista, Rose, Christopher   +2 more
core   +2 more sources