Results 81 to 90 of about 2,685,828 (313)

Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways

open access: yesShipin gongye ke-ji
Objective: The main regulated cell death (RCD) signaling pathway of Cordyceps militaris (XG) water extract that affects the growth activity of the human gastric cancer cell line BGC-823 was analyzed and predicted using transcriptome sequencing technology.
Mingqi CUI   +5 more
doaj   +1 more source

Economic Value of Life in Iran: The Human Capital Approach. [PDF]

open access: yesIran J Public Health, 2021
Basakha M   +3 more
europepmc   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Environmental Sustainability Initiatives in the Operating Room: A Scoping Review

open access: yesAnnals of Surgery Open
The global healthcare industry has a substantial environmental footprint and therefore has a responsibility to decrease its impact. Changes to increase sustainability will only occur if healthcare providers (HCPs) and decision-makers understand and ...
Emre Gorgun, MD   +6 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Application of discrete choice experiments to estimate value of life: a national study protocol in Iran. [PDF]

open access: yesCost Eff Resour Alloc, 2021
Mirzaee N   +5 more
europepmc   +1 more source

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