Results 11 to 20 of about 3,646 (171)

Development of a multiplex recombinase polymerase amplification combined with a DNA strip for the rapid detection of Enterococcus faecium, Enterococcus faecalis, and vancomycin resistance genes [PDF]

PeerJ
Background Vancomycin-resistant enterococci (VRE), particularly Enterococcus faecium and E. faecalis, are responsible for various human infections and represent a significant global public health concern in both nosocomial and community settings.
Pattharasak Thaweesub, Aroonlug Lulitanond, Aroonwadee Chanawong, Setchanaphong Thitiwatrueangrut, Pheeraphon Khlaichanthong, Patcharaporn Tippayawat, Molin Wongwattanakul, Orapan Sripichai, Arpasiri Srisrattakarn   +8 more
doaj   +3 more sources

Genomic epidemiology of Enterococcus faecium bloodstream infections during a VanB-type VRE peak reveals an oligoclonal scenario: an observational study at a German university hospital (2017–2022) [PDF]

Journal of Clinical Microbiology
A substantial and rapid increase, followed by a sharp decline in vanB-type vancomycin-resistant Enterococcus faecium (VRE), occurred in Germany in the late 2010s.
Leonard Knegendorf, Anna Sommer, Claas Baier, Robert E. Weber, Martin A. Fischer, Guido Werner, Stefan Ziesing, Dirk Schlüter   +7 more
doaj   +2 more sources

Real-time PCR for the rapid detection of vanA, vanB and vanM genes

Journal of Microbiology, Immunology and Infection, 2020
Background/Purpose: To evaluate the ability of quadruple Taqman probe real-time PCR to the detection of vanA, vanB and vanM in enterococcal isolates. Methods: A total of 343 strains, including 253 vancomycin-resistant enterococcus (VRE) strains and 90 ...
Yuan-Hui He, Gen-Jie Ruan, Hui Hao, Feng Xue, Ya-Kun Ma, Sai-Nan Zhu, Bo Zheng   +6 more
doaj   +3 more sources

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme [PDF]

Advanced Science, Volume 13, Issue 6, 30 January 2026.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun, Chao Dou, Weizhu Yan, Pengpeng Chen, Lu Zhang, Dan Zhou, Yanhui Zheng, Zhaolin Long, Shoujie Li, Xiaoqing Xu, Qiuxia Huang, Xiaofeng Zhu, Wei Cheng   +12 more
wiley   +2 more sources

Investigation of vanA and vanB Genes in Vancomycin-Susceptible Enterococcal Strains

Journal of Global Antimicrobial Resistance
AIM: The study aimed to investigate vanA/vanB resistance genes and to determine the frequency of vancomycin-variable enterococci(VVE). BACKGROUND: Enterococci that are phenotypically-susceptible to vancomycin but harbor glycopeptide resistance genes are ...
Merve Gürler, Zeynep Ceren Karahan, Ebru Evren, Fazıl Alper Tekeli   +3 more
doaj   +2 more sources

Evaluation of sample pooling using Xpert Carba-R and Xpert vanA/vanB PCR for screening of carbapenemase-producing Enterobacterales and vancomycin-resistant Enterococcus colonization [PDF]

Microbiology Spectrum
Screening for carbapenemase-producing Enterobacterales (CPE) and vancomycin-resistant Enterococcus (VRE) colonization among hospitalized patients is a standard infection control procedure that also guides appropriate antibiotic treatment in healthcare ...
Danielle Keidar-Friedman, Larissa Gil, Anka Tsur, Tal Brosh-Nissimov, Yehuda Carmeli, Boaz David Rosenfeld, Nadav Sorek   +6 more
doaj   +2 more sources

The Structural Basis for Induction of VanB Resistance [PDF]

Journal of the American Chemical Society, 2002
Because teicoplanin and vancomycin are the last line of defense for many bacterial infections, the emergence of resistance to glycopeptide antibiotics in enterococci and streptococci has aroused concern. Despite their similarity in terms of structure and mechanism of action, vancomycin induces the expression of genes that leads to bacterial resistance,
Steven D, Dong, Markus, Oberthür, Heather C, Losey, John W, Anderson, Ulrike S, Eggert, Mark W, Peczuh, Christopher T, Walsh, Daniel, Kahne   +7 more
openaire   +3 more sources

VanB-VanC1 Enterococcus gallinarum, Italy

Emerging Infectious Diseases, 2005
To the Editor: We report detecting a vanB determinant in Enterococcus gallinarum in poultry in Italy. High-level vanA-mediated glycopeptide resistance has been described for E. gallinarum and E. casseliflavus (1–4), and vanB-mediated vancomycin resistance has been frequently described for E. faecalis and E. faecium. However, vanB-mediated resistance in
Caterina Mammina, Anna Maria Di Noto, Antonella Costa, Antonino Nastasi   +3 more
doaj   +5 more sources

The changing epidemiology of VanB Enterococcus faecium in Poland [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2018
Increasing prevalence of VanB Enterococcus faecium in Polish hospitals reported to National Reference Centre for Susceptibility Testing (NRCST) prompted us to investigate the basis of this phenomenon. Two-hundred seventy-eight E. faecium isolates of VanB phenotype from the period 1999 to 2010 obtained by NRCST were investigated by multilocus sequence ...
Ewa Sadowy, Iwona Gawryszewska, Alicja Kuch, Dorota Żabicka, Waleria Hryniewicz   +4 more
openaire   +2 more sources

Regulation of VanA- and VanB-Type Glycopeptide Resistance in Enterococci [PDF]

Antimicrobial Agents and Chemotherapy, 2001
Glycopeptide antibiotics vancomycin and teicoplanin inhibit cell wall synthesis by forming complexes with the peptidyl-d-alanyl–d-alanine (d-Ala–d-Ala) termini of peptidoglycan precursors at the cell surface ([33][1]).
M, Arthur, R, Quintiliani
openaire   +2 more sources