Results 31 to 40 of about 4,946 (199)

Determination of a Tentative Epidemiological Cut-Off Value (ECOFF) for Dalbavancin and Enterococcus faecium

Antibiotics, 2021
Dalbavancin is a lipoglycopeptide antibiotic that shows potent activity against Gram-positive bacteria. It circumvents vanB-type glycopeptide resistance mechanisms; however, data on the in vitro activity of dalbavancin for Enterococcus faecium (E ...
Robert E. Weber, Carola Fleige, Franziska Layer, Bernd Neumann, Michael Kresken, Guido Werner   +5 more
doaj   +1 more source

Rapid Detection of VanA/B-Producing Vancomycin-Resistant Enterococci Using Lateral Flow Immunoassay

Diagnostics, 2021
Vancomycin-resistant enterococci (VREs) have become one of the most important nosocomial pathogens worldwide, associated with increased treatment costs, prolonged hospital stays and high mortality.
Saoussen Oueslati, Camille Gonzalez, Hervé Volland, Vincent Cattoir, Sandrine Bernabeu, Delphine Girlich, Duncan Dulac, Marc Plaisance, Laure Boutigny, Laurent Dortet, Stéphanie Simon, Thierry Naas   +11 more
doaj   +1 more source

Regulation of VanA- and VanB-Type Glycopeptide Resistance in Enterococci [PDF]

Antimicrobial Agents and Chemotherapy, 2001
Glycopeptide antibiotics vancomycin and teicoplanin inhibit cell wall synthesis by forming complexes with the peptidyl-d-alanyl–d-alanine (d-Ala–d-Ala) termini of peptidoglycan precursors at the cell surface ([33][1]).
M, Arthur, R, Quintiliani
openaire   +2 more sources

Heterogeneous expression of glycopeptide resistance in enterococci associated with transfer of vanB [PDF]

Antimicrobial Agents and Chemotherapy, 1997
In mating experiments using a clinical strain that constitutively expresses vanB-encoded glycopeptide resistance, resistance transfer was detectable at a frequency of <10(-7) transconjugants/donor. Vancomycin MICs for transconjugants were 2- to 10-fold lower than those for the donor; both inducibly and constitutively resistant transconjugants were ...
M K, Hayden, R N, Picken, D F, Sahm
openaire   +2 more sources

735. Vancomycin-Resistant vanB- and vanA/vanB-type Enterococcus faecium Causing Invasive Infections in Adult Patients in Chile

Open Forum Infectious Diseases, 2023
Abstract Background Vancomycin-resistant enterococci has increased globally in recent decades, with Enterococcus faecium (VREfm) being the most prevalent species. Although the prevalence of VREfm in Chile is high (∼70%), its molecular epidemiology is not well-described.
Diaz, Lorena, Rivas, Lina M, Martinez, Jose R W, Peters, Anne S, Riquelme, Maria Paz, de Paula Baptista, Rodrigo, Panesso, Diana, Tran, Truc T, Singh, Kavindra, Miller, William R, Antolinez, Yohanna, Sanfurgo, Valentina, Bugueno, Francisca, Quiroz, Valeria E, Soto, Katherine D, Quesille-Villalobos, Ana M, Rojas, Pamela, Rioseco, Maria, Moreno, Juan, Rafael, Araos, Arias, Cesar A, Munita, José M, Garcia, Patricia   +22 more
openaire   +1 more source

Concentration and reduction efficiency of vancomycin-resistant heterotrophic bacteria and vanA and vanB genes in wastewater treatment unit processes

Journal of Global Antimicrobial Resistance, 2022
Objectives: This study elucidated the distribution and fate of vancomycin (VCM)-resistant heterotrophic bacteria (HTB) and resistance genes, vanA and vanB, during each treatment unit process of a wastewater treatment plant (WWTP).
Takashi Furukawa, Tohru Mekata, Mohan Amarasiri, Kazunari Sei   +3 more
doaj   +1 more source

Case-case-control study on factors associated with vanB vancomycin-resistant and vancomycin-susceptible enterococcal bacteraemia [PDF]

, 2014
BACKGROUND: Enterococci are a major cause of healthcare-associated infection. In Australia, vanB vancomycin-resistant enterococci (VRE) is the predominant genotype. There are limited data on the factors linked to vanB VRE bacteraemia. This study aimed to
Howden, BP, Nation, RL, Grayson, ML, Kong, DCM, Peel, T, Spelman, D, Cheah, ALY   +6 more
core   +4 more sources

Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan

BMC Microbiology, 2018
Background VanB-type vancomycin (VAN) resistance gene clusters confer VAN resistances on Enterococcus spp. over a wide range of MIC levels (MIC = 4–1000 mg/L).
Yusuke Hashimoto, Jun Kurushima, Takahiro Nomura, Koichi Tanimoto, Kiyoko Tamai, Hideji Yanagisawa, Komei Shirabe, Yasuyoshi Ike, Haruyoshi Tomita   +8 more
doaj   +1 more source

Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida [PDF]

, 2023
In the United States, vanB-mediated resistance in enterococci is rare. We characterized three sequence type (ST) 6, vancomycin-resistant Enterococcus faecalis isolates causing bacteremia in unique patients in spatiotemporally distinct settings.
Rydell, Kirsten B, Contreras, German A., Simar, Shelby, Hanson, Blake M, Dinh, An Q, Cifuentes, Renzo O., Cifuentes, Renzo O, Munita, Jose M, Contreras, German A, Shelburne, Samuel A., Arias, Cesar A, Munita, Jose M., Shelburne, Samuel, Simar, Shelby R., Hanson, Blake, Dinh, An Q., Arias, Cesar A., Panesso, Diana, Abbo, Lilian, Dinh, An, Contreras, German, Axell House, Dierdre B., Hanson, Blake M., Sahasrabhojane, Pranoti, Tran, Truc T., Axell-House, Dierdre B, Abbo, Lilian M, Savidge, Tor, Arias, Cesar, Axell-House, Dierdre, Axell-House, Dierdre B., Tran, Truc T, Shelburne, Samuel A, Rydell, Kirsten B., Savidge, Torj, Cifuentes. Renzo, Tran, Truc, Abbo, Lilian M., Simar, Shelby R, Rydell, Kirsten   +39 more
core   +1 more source

Chemotranscriptomic Profiling Defines Drug-Specific Signatures of the Glycopeptide Antibiotics Dalbavancin, Vancomycin and Chlorobiphenyl-Vancomycin in a VanB-Type-Resistant Streptomycete

Frontiers in Microbiology, 2021
Dalbavancin, vancomycin and chlorobiphenyl-vancomycin share a high degree of structural similarity and the same primary mode of drug action. All inhibit bacterial cell wall biosynthesis through complexation with intermediates in peptidoglycan ...
Andy Hesketh, Giselda Bucca, Colin P. Smith, Hee-Jeon Hong   +3 more
doaj   +1 more source