Results 71 to 80 of about 302,754 (340)

Laboratory correlation between vancomycin levels and serum creatinine in the nephrotoxicity of vancomycin

Cogent Medicine, 2016
Reports about relationship on renal function and vancomycin exposure are conflicted and limited. Goals: To identify if high serum vancomycin levels precede changes in serum creatinine or if it is secondary to reduced glomerular filtration and to analyze ...
Luiza K.R.P. Araújo, Yule A. Ueno, Thais Gentil, Emília M.D. Soeiro, Isac Castro, Sandra M. Laranja, Benedito Jorge Pereira   +6 more
doaj   +1 more source

Measurement of teicoplanin by liquid chromatography-tandem mass spectrometry:development of a novel method [PDF]

, 2012
Teicoplanin is an antibiotic used for the treatment of endocarditis, osteomyelitis, septic arthritis and methicillin-resistant Staphylococcus aureus. Teicoplanin is emerging as a suitable alternative antibiotic to vancomycin, where their trough serum ...
Bailey, Lisa M, Davison, Andrew S, Dutton, John, Fung, Francis H Y, Hopkins, John P P, Tang, Jonathan C Y   +5 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Renal Protective Effect of Sulbutiamine, Thiamine, Riboflavin and their Combinations on Vancomycin-Induced Acute Renal Failure in Male Rats

Iraqi Journal of Pharmaceutical Sciences
Background: The main mechanisms thought to be involved in the pathophysiology of acute renal failure with vancomycin treatment are oxidative stress, inflammation and apoptosis.  In this study we evaluated the potential effects of sulbutiamine, thiamine,
Dayan K. Jabbar , Ghaith A. Jasim, Muthana I. Al-Ezzi   +2 more
doaj   +1 more source

Immunoglobulin E-mediated hypersensitivity reaction after intraperitoneal administration of vancomycin

Kidney Research and Clinical Practice, 2015
Intraperitoneal (IP) vancomycin is widely used to treat Gram-positive peritonitis associated with peritoneal dialysis. There have been two cases of red man syndrome (RMS), a vancomycin-specific nonimmunologic reaction, associated with IP vancomycin ...
Mun-Ju Hwang, Jun-Young Do, Eun-Woo Choi, Joon-Hyuk Seo, Yoon-Jung Nam, Kyung-Woo Yoon, Jong-Won Park, Kyu-Hyang Cho, Seok-Hui Kang, Hyun-Jung Jin   +9 more
doaj   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Vancomycin Removal During High-Volume Peritoneal Dialysis in Acute Kidney Injury Patients: A Prospective Cohort Clinical Study

Kidney International Reports, 2019
Introduction: Vancomycin pharmacokinetic data in patients with acute kidney injury (AKI) on high-volume peritoneal dialysis (HVPD) are lacking. The aims were to study the pharmacokinetics of i.v.
Daniela Ponce, Welder Zamoner, Fernanda Moreira Freitas, André Balbi, Linda Awdishu   +4 more
doaj   +1 more source

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Clinical failure of vancomycin treatment of Staphylococcus aureus infection in a tertiary care hospital in southern Brazil

Brazilian Journal of Infectious Diseases
We describe a case of clinical failure of vancomycin treatment of Staphylococcus aureus infection and the laboratory characteristics of the organism in a tertiary referral university hospital in southern Brazil.
Larissa Lutz, Adão Machado, Nadia Kuplich, Afonso Luís Barth   +3 more
doaj   +1 more source