Results 71 to 80 of about 182,488 (255)

Heterogeneous vancomycin resistance in Staphylococcus aureus does not predict development of vancomycin resistance upon vancomycin pressure

, 2022
International audienceAbstract Background It is unclear whether Staphylococcus aureus with heterogeneous intermediate vancomycin resistance (hVISA) can develop vancomycin resistance faster than vancomycin-susceptible S. aureus (VSSA) strains.
Gaillard, Tiphaine, Laurent, Frédéric, Dumitrescu, Oana, Naceur, Oilida, Tristan, Anne, Butin, Marine, Martra, Annie, Rasigade, Jean-Philippe, Dupieux-Chabert, Céline, Bouveyron, Caroline, Vandenesch, François, Lina, Gérard, Bes, Michèle, Tiphaine Gaillard, Annie Martra, Frédéric Laurent, Caroline Bouveyron, Gérard Lina, François Vandenesch, Jean-Philippe Rasigade, Anne Tristan, Michèle Bes, Oilida Naceur, Marine Butin, Oana Dumitrescu, Céline Dupieux-Chabert   +25 more
core   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

Advanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang, Xin Li, Ying Xiong, Xin Wang, Ying‐Wei Yang   +4 more
wiley   +1 more source

Appropriate use of vancomycin in a cardiac surgical unit

Journal of Cardiothoracic Surgery
Background Antibiotic resistance is a rapidly growing problem. Methicillin-resistant staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) are major worries, particularly in developing nations where cost-effectiveness is essential.
Sanaa Mekdad, Leenah Alsayed, Suzan Alkhalaif   +2 more
doaj   +1 more source

Activity of simulated serum concentrations of daptomycin versus vancomycin during the first 24h of treatment in the presence of physiological albumin concentrations against vancomycin-susceptible, -tolerant or -intermediate-resistant Staphylococcus aureus

, 2011
In order to determine whether reduced susceptibility or tolerance to vancomycin in Staphylococcus aureus influences the activity of daptomycin by simulating serum concentrations in the first 24h of treatment in the presence of physiological ...
Fabio Cafini, Giménez, María José, Alou Cervera, Luis, Alou, Luis, Natalia González, Roy Cleeland, Aguilar, Lorenzo, González Hidalgo, Natalia, Cafini, Fabio, María-José Giménez, González, Natalia, Luis Alou, Torrico, Martha, Giménez, María-José, José Prieto, Prieto Prieto, José, Prieto, José, Sevillano, David, Martha Torrico, Cleeland, Roy, Lorenzo Aguilar, Sevillano Fernández, David, David Sevillano   +22 more
core   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Acetaldehyde Contributes to the Disease‐Alleviating Effects of Kurarinone in Experimental Autoimmune Encephalomyelitis

Advanced Science, EarlyView.
Kurarinone ameliorates EAE via the gut microbiota‐indole‐3‐acetaldehyde‐AhR axis. Kurarinone reshapes gut microbiota and increases Akkermansia muciniphila, which promotes intestinal indole‐3‐acetaldehyde production. Indole‐3‐acetaldehyde crosses the intestinal barrier, activates AhR in CD4+ T cells, upregulates SOCS1/3, inhibits JAK2 and STAT3/4 ...
Xinyan Han, Jiaqi Ding, Zonghao Pan, Weitai He, Xue Kang, Cong Zhao, Yi Li, Di Wu, Hongzeng Li, Kaixi Ren, Jiaji Lin, Jun Guo   +11 more
wiley   +1 more source

A new approach to Vancomycin utilization evaluation: A cross-sectional study in intensive care unit

Journal of Research in Pharmacy Practice, 2016
Objective: The risk of methicillin-resistant Staphylococcus aureus infections in Intensive Care Unit (ICU) is increasing in recent years with high rate of morbidity and mortality.
Atefeh Mahmoodian, Saeed Abbasi, Shadi Farsaei   +2 more
doaj   +1 more source

Vancomycin-stressed Staphylococcus aureus extracellular vesicles hijack macrophage autophagy to enhance bacterial intracellular survival

Methicillin-resistant Staphylococcus aureus (MRSA) is a major multidrug-resistant human pathogen. Vancomycin has long been the cornerstone therapy for invasive MRSA infections.
Shanshan Zhang (50616), Bing Lu (178293), Yuanyuan Dai (714579), Yujie Wei (1502143), Xiaoling Ma (325873), Zhengchao Nie (21433378), Chenggong Guo (24380457), Xueer Liu (11429980), Wenjin Wang (1721389), Pengsheng Ding (11599464), Gan Liu (1899271), Wenjiao Chang (325874), Lan Shi (6937832)   +12 more
core   +1 more source

Tackling vancomycin-resistant bacteria with ‘lipophilic–vancomycin–carbohydrate conjugates’

, 2014
Vancomycin, a glycopeptide antibiotic, has long been a drug of choice for life-threatening Gram-positive bacterial infections. Vancomycin confers its antibacterial activity by inhibiting bacterial cell wall biosynthesis.
Chandradhish Ghosh, Jayanta Haldar, Konai, Mohini M, Venkateswarlu Yarlagadda, Goutham B Manjunath, Manjunath, Goutham B, Ghosh, Chandradhish, Yarlagadda, Venkateswarlu, Mohini M Konai, Haldar, Jayanta   +9 more
core   +1 more source

Reasons for the cessation of vancomycin treatment and adverse events of vancomycin.

, 2023
Reasons for the cessation of vancomycin treatment and adverse events of vancomycin.
Masae Sekido (16914152), Natsumi Okada (150162), Matoka Okamoto (16914149), Masakazu Abe (732077), Michiko Tanaka (2709046), Tatsuro Tamatukuri (16914155), Masayuki Yoshikawa (1561963), Hideki Sugita (16914146), Eisuke Inoue (400274), Hironori Tanaka (8744841), Yuika Naito (16914158)   +10 more
core   +1 more source