Results 211 to 220 of about 132,718 (290)

Pharmacokinetic Analysis of Intravenous Push Cefepime in Critically Ill Patients With Sepsis

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Intravenous push (IVP) administration of cefepime increases ease of preparation and limits the need for small volume parenterals. The data on IVP pharmacokinetic/pharmacodynamic (PK/PD) parameters are limited, but may be especially relevant in critically ill patients with altered PK/PD for time‐dependent antibiotics like cefepime ...
Susan E. Smith   +8 more
wiley   +1 more source

Prevalence of ESBL-producing Escherichia coli from different canine populations in Italy [PDF]

open access: yes, 2016
DOTTO, GIORGIA   +5 more
core   +1 more source

Antimicrobial Secondary Metabolites From Rhizosphere‐Associated Streptomyces Species in Northern Nigerian Agricultural Soils: Genomic Mining and Bioactivity Assessment

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Nigerian agricultural soils harbour diverse Streptomyces species producing novel antimicrobial secondary metabolites. Genomic mining revealed 187 biosynthetic gene clusters, leading to isolation of twelve new compounds with potent activity against multidrug‐resistant pathogens, including MRSA and vancomycin‐resistant Enterococcus. ABSTRACT Streptomyces
David Adeiza Zakari   +4 more
wiley   +1 more source

High Resistance and Biofilm Tolerance to Antimicrobials of Marine Bacteria From Brazilian Deep‐Sea Sediment

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Antimicrobial resistance and biofilm‐specific tolerance of cultivable Pseudomonas, Bacillus, Brevibacillus and Paenibacillus isolated from deep‐sea sediments of a methane‐seep area off the Southern Brazilian coast. These findings underscore the role of deep‐sea environments as potential reservoirs for antimicrobial‐resistant bacteria (ARB) and ...
Amanda Simão Dias   +2 more
wiley   +1 more source

Tissue‐retained needles in people who inject drugs: A systematic review of case reports and series on clinical presentations, complications and management

open access: yesAddiction, Volume 121, Issue 6, Page 1381-1397, June 2026.
Abstract Background and aims Tissue‐retained needles from intravenous drug use can cause rare but severe complications, ranging from local to systemic infections to needle embolization. Due to the limited evidence and the lack of epidemiological studies on the issue, we systematically reviewed the literature focusing on case reports and case series on ...
Heidi Laukkala   +7 more
wiley   +1 more source

Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 11, Page 1487-1494, June 2026.
This multicenter, observational study reveals distinct alterations in the microbial spectrum of spontaneous bacterial peritonitis (SBP) associated with proton pump inhibitor use. These results are especially relevant for guiding empiric antibiotic therapy of SBP.
Philip Kitchen   +13 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

open access: yesAdvanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, Volume 13, Issue 28, 18 May 2026.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

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