Results 41 to 50 of about 1,206 (173)

Genomic characterization of Microbacterium meiriae sp. nov., a novel bacterium isolated from the International Space Station [PDF]

Scientific Reports
During the microbial surveillance of the International Space Station (ISS) in April 2018, four Gram-stain positive bacterial strains, designated as F6_8S_P_2BT, F6_8S_P_3A, F6_8S_P_3B and F6_8S_P_3C, belonging to the genus Microbacterium were isolated ...
Fathi Karouia, Lorraine Christine de Oliveira, Asif Hameed, Anna Simpson, Nitin Singh, Punchappady D. Rekha, Christopher E. Mason, Kasthuri Venkateswaran   +7 more
doaj   +2 more sources

The Biochemistry of VapBC Toxin-Antitoxins [PDF]

, 2011
The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey ...
Joanna L. McKenzie
openalex   +4 more sources

The endogenous Coxiella burnetii plasmid encodes a functional toxin–antitoxin system

Molecular Microbiology, Volume 118, Issue 6, Page 744-764, December 2022., 2022
Coxiella burnetii is an obligate intracellular bacterium and causative agent of Q fever. Here we report that the C. burnetii genome encodes 11 toxin–antitoxin systems, which is highly unusual for intracellular bacteria, and that one TA system is encoded on the large endogenous plasmid found in almost all C. burnetii isolates.
Shaun Wachter, Diane C. Cockrell, Heather E. Miller, Kimmo Virtaneva, Kishore Kanakabandi, Benjamin Darwitz, Robert A. Heinzen, Paul A. Beare   +7 more
wiley   +1 more source

RepC_soli: a novel promiscuous plasmid type of Rhodobacteraceae mediates horizontal transfer of antibiotic resistances in the ocean

Environmental Microbiology, Volume 23, Issue 9, Page 5395-5411, September 2021., 2021
Summary Alphaproteobacteria are typically characterized by a multipartite genome organization with a chromosome, stable chromids and accessory plasmids. Extrachromosomal elements determine the lifestyle of roseobacters and their horizontal transfer was previously correlated with rapid adaptations to novel ecological niches.
Lukas Birmes, Heike M. Freese, Jörn Petersen   +2 more
wiley   +1 more source

Legume–rhizobium dance: an agricultural tool that could be improved?

Microbial Biotechnology, Volume 14, Issue 5, Page 1897-1917, September 2021., 2021
The present review describes the mechanisms involved in the regulation of the entire legume‐rhizobium symbiotic process and the strategies and tools of bacteria for reaching the nitrogen‐fixing state inside the nodule. Also, we revised different approaches to improve the nodulation process for a better crop yield.
Laura A. Basile, Viviana C. Lepek
wiley   +1 more source

Prokaryote toxin–antitoxin modules: Complex regulation of an unclear function

Protein Science, Volume 30, Issue 6, Page 1103-1113, June 2021., 2021
Abstract Toxin–antitoxin (TA) modules are small operons in bacteria and archaea that encode a metabolic inhibitor (toxin) and a matching regulatory protein (antitoxin). While their biochemical activities are often well defined, their biological functions remain unclear. In Type II TA modules, the most common class, both toxin and antitoxin are proteins,
Pieter De Bruyn, Yana Girardin, Remy Loris   +2 more
wiley   +1 more source

Transcriptional and proteolytic regulation of the toxin-antitoxin locus vapBC10 (ssr2962/slr1767) on the chromosome of Synechocystis sp. PCC 6803. [PDF]

PLoS ONE, 2013
VapBC toxin-antitoxin (TA) systems are defined by the association of a PIN-domain toxin with a DNA-binding antitoxin, and are thought to play important physiological roles in bacteria and archaea.
Degang Ning, Shuibing Liu, Weidong Xu, Qiang Zhuang, Chongwei Wen, Xiaoxia Tang   +5 more
doaj   +1 more source

Characterisation of VapBC Toxin-Antitoxins from Mycobacterium tuberculosis [PDF]

, 2013
Toxin-antitoxin (TA) systems were identified more than 20 years ago on the mini F plasmid of Escherichia coli as plasmid stability elements; components responsible for purging bacterial cells that lack the plasmid from the population.
Abigail V. Sharrock
openalex   +3 more sources

Structure‐based design of peptides that trigger Streptococcus pneumoniae cell death

The FEBS Journal, Volume 288, Issue 5, Page 1546-1564, March 2021., 2021
HigBA complex shows a crossed‐scissor interface with two intermolecular β‐sheets at both the N and C termini of the HigA antitoxin. The crossed‐scissor constitutes a new type of interface between HigB and HigA. We report a unique structure of the Streptococcus pneumoniae HigBA system and a novel antimicrobial agent that activates HigB toxin, which ...
Sung‐Min Kang, Chenglong Jin, Do‐Hee Kim, Sung Jean Park, Sang‐Woo Han, Bong‐Jin Lee   +5 more
wiley   +1 more source

Isolation of persister cells within the biofilm and relative gene expression analysis of type II toxin/antitoxin system in Pseudomonas aeruginosa isolates in exponential and stationary phases

Journal of Global Antimicrobial Resistance, 2022
: Objectives: Chronic infections and treatment failure are concerning issues in patients with Pseudomonas aeruginosa infections. Persister cell formation in biofilm is considered a key reason for antibiotic resistance and treatment failure.
Rezvan Golmoradi Zadeh, Behrooz Sadeghi Kalani, Marzie Mahdizade Ari, Malihe Talebi, Shabnam Razavi, Faramarz Masjedian Jazi   +5 more
doaj   +1 more source