Results 21 to 30 of about 721 (155)

Transcriptome profiling of Nudix hydrolase gene deletions in the thermoacidophilic archaeon Sulfolobus acidocaldarius [PDF]

open access: yesFrontiers in Microbiology, 2023
Nudix hydrolases comprise a large and ubiquitous protein superfamily that catalyzes the hydrolysis of a nucleoside diphosphate linked to another moiety X (Nudix).
Ruth Breuer   +5 more
doaj   +2 more sources

Role of VapBC4 toxin-antitoxin system of Sulfolobus acidocaldarius in heat stress adaptation [PDF]

open access: yesmBio
Toxin-antitoxin (TA) systems are important for stress adaptation in prokaryotes, including persistence, antibiotic resistance, pathogenicity, and biofilm formation.
Arghya Bhowmick   +7 more
doaj   +2 more sources

Genomic profiling of Morganella morganii: insights into antibiotic resistance genes, pathogenicity islands, and toxin-antitoxin systems [PDF]

open access: yesMicrobiology Spectrum
Morganella morganii is an opportunistic pathogen affecting immunocompromised and hospitalized intensive care patients. It colonizes diverse environments and exhibits multidrug resistance.
Tosin Yetunde Senbadejo   +2 more
doaj   +2 more sources

Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes

open access: yes, 2017
Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or protein translation.
Bendtsen, Kirstine L   +1 more
openaire   +5 more sources

Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly

open access: yesJournal of Molecular Biology, 2011
Toxin-antitoxin (TA) loci are common in archaea and prokaryotes and allow cells to rapidly adapt to changing environmental conditions through release of active regulators of metabolism. Many toxins are endonucleases that target cellular mRNA and tRNAs, while the antitoxins tightly wrap around the toxins to inhibit them under normal circumstances.
Dienemann C   +4 more
openaire   +4 more sources

Clonagem, expressão e caracterização inicial do módulo VapBC-4 de >i<Leptospira interrogans >/i<sorovar Copenhageni

open access: yes, 2023
A leptospirose é uma zoonose causada pela bactéria espiroqueta aeróbia do gênero Leptospira, sendo a Leptospira interrogans sorovar Copenhageni uma das maiores responsáveis pelos casos em seres humanos da doença no Brasil.
Azevedo, Bruna Oliveira Pigatto
openaire   +2 more sources

A vapBC-type toxin-antitoxin module of Sinorhizobium meliloti influences symbiotic efficiency and nodule senescence of Medicago sativa.

open access: yesEnvironmental microbiology, 2014
The symbiotic nitrogen-fixing soil bacterium Sinorhizobium meliloti carries a large number of toxin-antitoxin (TA) modules both on the chromosome and megaplasmids. One of them, the vapBC-5 module that belongs to the type II systems was characterized here. It encodes an active toxin vapC-5, and was shown to be controlled negatively by the complex of its
Lipuma, Justine   +7 more
core   +5 more sources

Genomic characterization of Microbacterium meiriae sp. nov., a novel bacterium isolated from the International Space Station [PDF]

open access: yesScientific Reports
During the microbial surveillance of the International Space Station (ISS) in April 2018, four Gram-stain positive bacterial strains, designated as F6_8S_P_2BT, F6_8S_P_3A, F6_8S_P_3B and F6_8S_P_3C, belonging to the genus Microbacterium were isolated ...
Fathi Karouia   +7 more
doaj   +2 more sources

The VapBC Toxin-Antitoxin systems : regulators of the nitrogen-fixing symbiosis Rhizobium-Legume

open access: yes, 2020
Lors de la symbiose fixatrice d’azote entre la légumineuse modèle Medicago truncatula et la rhizobiacée Sinorhizobium meliloti, les bactéries, différenciées en bactéroïdes dans la nodosité, réduisent l’azote atmosphérique (N2) en ammoniac (NH3), directement assimilable par la plante.
Syska, Camille
openaire   +2 more sources

Estudos sobre o módulo toxina-antitoxina VapBC 1 de >i<Leptospira interrogans>/i< sorovar Copenhageni

open access: yes
A leptospirose é uma zoonose de distribuição mundial e a linhagem L. interrogans sorovar Copenhageni é a responsável pelo maior número de casos humanos de leptospirose no Brasil. Seu genoma foi sequenciado, contribuindo para o entendimento dos mecanismos
Damiano, Deborah Kohn
openaire   +2 more sources

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