Transcriptome profiling of Nudix hydrolase gene deletions in the thermoacidophilic archaeon Sulfolobus acidocaldarius [PDF]
Frontiers in Microbiology, 2023 Nudix hydrolases comprise a large and ubiquitous protein superfamily that catalyzes the hydrolysis of a nucleoside diphosphate linked to another moiety X (Nudix).
Ruth Breuer +5 more
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Insights into toxin-antitoxin systems in the genus Bifidobacterium [PDF]
Applied and Environmental MicrobiologyToxin-antitoxin (TA) systems are widespread genetic modules in prokaryotes, implicated in diverse functions including stress adaptation, genome stability, and virulence.
Claudia Lefimil, Paula Bustamante
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Clonagem, expressão e caracterização inicial do módulo VapBC-4 de >i<Leptospira interrogans >/i<sorovar Copenhageni [PDF]
, 2023 A leptospirose é uma zoonose causada pela bactéria espiroqueta aeróbia do gênero Leptospira, sendo a Leptospira interrogans sorovar Copenhageni uma das maiores responsáveis pelos casos em seres humanos da doença no Brasil.
Azevedo, Bruna Oliveira Pigatto
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Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly [PDF]
Journal of Molecular Biology, 2011 Toxin-antitoxin (TA) loci are common in archaea and prokaryotes and allow cells to rapidly adapt to changing environmental conditions through release of active regulators of metabolism. Many toxins are endonucleases that target cellular mRNA and tRNAs, while the antitoxins tightly wrap around the toxins to inhibit them under normal circumstances.
Dienemann C +4 more
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A vapBC-type toxin-antitoxin module of Sinorhizobium meliloti influences symbiotic efficiency and nodule senescence of Medicago sativa. [PDF]
Environmental microbiology, 2014 The symbiotic nitrogen-fixing soil bacterium Sinorhizobium meliloti carries a large number of toxin-antitoxin (TA) modules both on the chromosome and megaplasmids. One of them, the vapBC-5 module that belongs to the type II systems was characterized here. It encodes an active toxin vapC-5, and was shown to be controlled negatively by the complex of its
Lipuma, Justine +7 more
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Role of VapBC4 toxin-antitoxin system of Sulfolobus acidocaldarius in heat stress adaptation [PDF]
mBioToxin-antitoxin (TA) systems are important for stress adaptation in prokaryotes, including persistence, antibiotic resistance, pathogenicity, and biofilm formation.
Arghya Bhowmick +7 more
doaj +2 more sources
Genomic profiling of Morganella morganii: insights into antibiotic resistance genes, pathogenicity islands, and toxin-antitoxin systems [PDF]
Microbiology SpectrumMorganella morganii is an opportunistic pathogen affecting immunocompromised and hospitalized intensive care patients. It colonizes diverse environments and exhibits multidrug resistance.
Tosin Yetunde Senbadejo +2 more
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The VapBC Toxin-Antitoxin systems : regulators of the nitrogen-fixing symbiosis Rhizobium-Legume [PDF]
, 2020 Lors de la symbiose fixatrice d’azote entre la légumineuse modèle Medicago truncatula et la rhizobiacée Sinorhizobium meliloti, les bactéries, différenciées en bactéroïdes dans la nodosité, réduisent l’azote atmosphérique (N2) en ammoniac (NH3), directement assimilable par la plante.
Syska, Camille
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Genomic characterization of Microbacterium meiriae sp. nov., a novel bacterium isolated from the International Space Station [PDF]
Scientific ReportsDuring the microbial surveillance of the International Space Station (ISS) in April 2018, four Gram-stain positive bacterial strains, designated as F6_8S_P_2BT, F6_8S_P_3A, F6_8S_P_3B and F6_8S_P_3C, belonging to the genus Microbacterium were isolated ...
Fathi Karouia +7 more
doaj +2 more sources
Estudos sobre o módulo toxina-antitoxina VapBC 1 de >i<Leptospira interrogans>/i< sorovar Copenhageni [PDF]
A leptospirose é uma zoonose de distribuição mundial e a linhagem L. interrogans sorovar Copenhageni é a responsável pelo maior número de casos humanos de leptospirose no Brasil. Seu genoma foi sequenciado, contribuindo para o entendimento dos mecanismos
Damiano, Deborah Kohn
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