Results 71 to 80 of about 1,206 (173)
Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles [PDF]
, 2011 The Acidianus hospitalis W1 genome consists of a minimally sized chromosome of about 2.13 Mb and a conjugative plasmid pAH1 and it is a host for the model filamentous lipothrixvirus AFV1.
Garrett, Roger A +8 more
core +4 more sources
Toxins VapC and PasB from Prokaryotic TA Modules Remain Active in Mammalian Cancer Cells
Toxins, 2014 Among the great number of addictive modules which have been discovered, only a few have been characterized. However, research concerning the adoption of toxins from these systems shows their great potential as a tool for molecular biology and medicine.
Łukasz Wieteska +3 more
doaj +1 more source
A nuclease specific to lepidopteran insects suppresses RNAi [PDF]
, 2018 More than 70% of all agricultural pests are insects in the order Lepidoptera, which, unlike other related insect orders, are not very sensitive to RNAi, limiting genetic studies of this insect group.
Christiaens, Olivier +6 more
core +2 more sources
Druggability of bacterial toxins-antitoxins [PDF]
, 2015 53 p.-8 fig.-3 tab.Type II (proteic) toxin-antitoxin (TA) operons are widely spread in bacteria and archaea. They are organized as operons in which, usually, the antitoxin gene precedes the cognate toxin gene.
Balsa, Dolors +2 more
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Translational regulation in mycobacteria and its implications for pathogenicity. [PDF]
, 2018 Protein synthesis is a fundamental requirement of all cells for survival and replication. To date, vast numbers of genetic and biochemical studies have been performed to address the mechanisms of translation and its regulation in Escherichia coli, but ...
Cortes, Teresa +2 more
core +1 more source
The ntrPR Operon of Sinorhizobium meliloti Is Organized and Functions as a Toxin-Antitoxin Module
Molecular Plant-Microbe Interactions, 2006 The chromosomal ntrPR operon of Sinorhizobium meliloti encodes a protein pair that forms a toxin-antitoxin (TA) module, the first characterized functional TA system in Rhizobiaceae. Similarly to other bacterial TA systems, the toxin gene ntrR is preceded
Monica Bodogai +5 more
doaj +1 more source
PLoS ONE, 2013 Mobilome of hyperthermophilic archaea dwelling in deep-sea hydrothermal vents is poorly characterized. To gain insight into genetic diversity and dynamics of mobile genetic elements in these environments we have sequenced five new plasmids from different
Mart Krupovic +4 more
doaj +1 more source
Neoteric advancement in TB drugs and an overview on the anti-tubercular role of peptides through computational approaches [PDF]
, 2017 Peptides of varied origins such as human immune cells and non-immune cells, bacteria, fungi, and venoms have been widely investigated as anti-tubercular agents for the replacement of existing anti-tubercular drugs in future.
Aarti, Chirom +7 more
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The Journal of biological chemistry, 2009 In prokaryotes, cognate toxin-antitoxin pairs have long been known, but no three-dimensional structure has been available for any given complex from Mycobacterium tuberculosis. Here we report the crystal structure and activity of a member of the VapBC family of complexes from M. tuberculosis.
Linda, Miallau +6 more
openaire +1 more source
살모넬라균 유래 VapBC 와 SehAB 독소-항독소 단백질의 구조적, 기능적 연구 [PDF]
, 2020 학위논문(박사)--서울대학교 대학원 :약학대학 약학과,2020. 2. 이봉진.세균성의 독소-항독소 시스템은 영양부족, 항생제 처리, 산화스트레스 등의 세포가 힘든 환경에 처했을 때 세포의 유지에 필수적인 역할을 하는 것으로 알려져 주목받고 있다. 독소-항독소 시스템은 항독소의 독소 저해 방식 혹은 항독소의 형태에 따라 6가지 독소-항독소 시스템이 존재한다. 그 중에서 타입 2 독소-항독소 시스템은 가장 많이 연구가 진행되었다.
박동원
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