Results 81 to 90 of about 1,206 (173)

Characterization of the Deep-Sea Streptomyces sp. SCSIO 02999 Derived VapC/VapB Toxin-Antitoxin System in Escherichia coli

open access: yesToxins, 2016
Toxin-antitoxin (TA) systems are small genetic elements that are ubiquitous in prokaryotes. Most studies on TA systems have focused on commensal and pathogenic bacteria; yet very few studies have focused on TAs in marine bacteria, especially those ...
Yunxue Guo   +4 more
doaj   +1 more source

Phenotypic responses to interspecies competition and commensalism in a naturally derived microbial co-culture [PDF]

open access: yes, 2018
The fundamental question of whether different microbial species will co-exist or compete in a given environment depends on context, composition and environmental constraints.
Barney, Brett M.   +11 more
core   +1 more source

Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding [PDF]

open access: yes, 2016
Expression of bacterial type II toxin-antitoxin (TA) systems is regulated at the transcriptional level through direct binding of the antitoxin to pseudo-palindromic sequences on operator DNA.
Bendtsen, Kirstine Louise   +6 more
core   +1 more source

Characterization of the genetic environment of blaESBL genes, integrons and toxin-antitoxin systems identified on large transferrable plasmids in multi-drug resistant Escherichia coli

open access: yesFrontiers in Microbiology, 2015
-Objectives:Previously 14 conjugative plasmids from multi-drug resistant (MDR) Escherichia coli from healthy humans and food-producing animals in Switzerland were sequenced.
JUAN eWANG   +5 more
doaj   +1 more source

Characterization and comparative overview of complete sequences of the first plasmids of Pandoraea across clinical and non-clinical strains

open access: yesFrontiers in Microbiology, 2016
To date, information on plasmid analysis in Pandoraea spp. is scarce. To address the gap of knowledge on this, the complete sequences of eight plasmids from Pandoraea spp.
Delicia Yong   +3 more
doaj   +1 more source

Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control [PDF]

open access: yes, 2015
The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
core   +1 more source

Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon [PDF]

open access: yes, 2013
The 2 465 177 bp genome of Sulfolobus islandicus LAL14/1, host of the model rudivirus SIRV2, was sequenced. Exhaustive comparative genomic analysis of S. islandicus LAL14/1 and the nine other completely sequenced S.
Bize, Ariane   +9 more
core   +4 more sources

Role of \u3ci\u3evapBC\u3c/i\u3e toxin–antitoxin loci in the thermal stress response of \u3ci\u3eSulfolobus solfataricus\u3c/i\u3e [PDF]

open access: yes, 2009
TA (toxin–antitoxin) loci are ubiquitous in prokaryotic microorganisms, including archaea, yet their physiological function is largely unknown. For example, preliminary reports have suggested that TA loci are microbial stress-response elements, although ...
Blum, Paul H.   +4 more
core   +3 more sources

Crystal Structure of VapBC-1 from Nontypeable \u3ci\u3eHaemophilus influenzae\u3c/i\u3e and the Effect of Pin Domain Mutations on Survival During Infection [PDF]

open access: yes, 2019
Toxin-antitoxin (TA) gene pairs have been identified in nearly all bacterial genomes sequenced to date and are thought to facilitate persistence and antibiotic tolerance.
Battaile, Kevin P.   +6 more
core   +1 more source

Targeting the Pin Domain of Type II Toxins Is a Novel Approach to Treat Infections Caused by Nontypeable \u3ci\u3eHaemophilus Influenzae\u3c/i\u3e [PDF]

open access: yes, 2019
Toxin-antitoxin (TA) gene pairs have been identified in nearly all bacterial genomes sequenced to date and are thought to facilitate persistence and antibiotic tolerance.
Molinaro, Ashley Lynne
core   +1 more source

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