Toxin-antitoxin (TA) systems are small genetic elements that are ubiquitous in prokaryotes. Most studies on TA systems have focused on commensal and pathogenic bacteria; yet very few studies have focused on TAs in marine bacteria, especially those ...
Yunxue Guo +4 more
doaj +1 more source
Phenotypic responses to interspecies competition and commensalism in a naturally derived microbial co-culture [PDF]
The fundamental question of whether different microbial species will co-exist or compete in a given environment depends on context, composition and environmental constraints.
Barney, Brett M. +11 more
core +1 more source
Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding [PDF]
Expression of bacterial type II toxin-antitoxin (TA) systems is regulated at the transcriptional level through direct binding of the antitoxin to pseudo-palindromic sequences on operator DNA.
Bendtsen, Kirstine Louise +6 more
core +1 more source
-Objectives:Previously 14 conjugative plasmids from multi-drug resistant (MDR) Escherichia coli from healthy humans and food-producing animals in Switzerland were sequenced.
JUAN eWANG +5 more
doaj +1 more source
To date, information on plasmid analysis in Pandoraea spp. is scarce. To address the gap of knowledge on this, the complete sequences of eight plasmids from Pandoraea spp.
Delicia Yong +3 more
doaj +1 more source
Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control [PDF]
The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
core +1 more source
Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon [PDF]
The 2 465 177 bp genome of Sulfolobus islandicus LAL14/1, host of the model rudivirus SIRV2, was sequenced. Exhaustive comparative genomic analysis of S. islandicus LAL14/1 and the nine other completely sequenced S.
Bize, Ariane +9 more
core +4 more sources
Role of \u3ci\u3evapBC\u3c/i\u3e toxin–antitoxin loci in the thermal stress response of \u3ci\u3eSulfolobus solfataricus\u3c/i\u3e [PDF]
TA (toxin–antitoxin) loci are ubiquitous in prokaryotic microorganisms, including archaea, yet their physiological function is largely unknown. For example, preliminary reports have suggested that TA loci are microbial stress-response elements, although ...
Blum, Paul H. +4 more
core +3 more sources
Crystal Structure of VapBC-1 from Nontypeable \u3ci\u3eHaemophilus influenzae\u3c/i\u3e and the Effect of Pin Domain Mutations on Survival During Infection [PDF]
Toxin-antitoxin (TA) gene pairs have been identified in nearly all bacterial genomes sequenced to date and are thought to facilitate persistence and antibiotic tolerance.
Battaile, Kevin P. +6 more
core +1 more source
Targeting the Pin Domain of Type II Toxins Is a Novel Approach to Treat Infections Caused by Nontypeable \u3ci\u3eHaemophilus Influenzae\u3c/i\u3e [PDF]
Toxin-antitoxin (TA) gene pairs have been identified in nearly all bacterial genomes sequenced to date and are thought to facilitate persistence and antibiotic tolerance.
Molinaro, Ashley Lynne
core +1 more source

