Results 101 to 110 of about 1,080 (170)

Analysis of the role of VapBC-type toxin-antitoxin modules in growth, stress tolerance and drug tolerance in mycobacteria [PDF]

, 2011
Forty seven of the toxin-antitoxin modules in the genome of Mycobacterium tuberculosis belong to the VapBC family in which the VapC toxin is a member of the PIN-domain protein family associated with nuclease activity.
Ahidjo, Bintou Ahmadou
core  

Characterization of a Toxin-Antitoxin Locus in Acinetobacter baumannii [PDF]

, 2016
Toxin-antitoxin (TA) systems are mechanisms of survival in many species of bacteria. In nontypeable Haemophilus influenzae (NTHi), the type II TA gene pair vapBC-1 encodes the VapB-1 antitoxin protein and the VapC-1 ribonuclease toxin.
Frost, Michaela
core  

VapCs of Mycobacterium tuberculosis Cleave RNAs Essential for Translation:VapCs of M. tuberculosis cleave tRNAs and 23S rRNA

, 2016
The major human pathogen Mycobacterium tuberculosis can survive in the host organism for decades without causing symptoms. A large cohort of Toxin-Antitoxin (TA) modules contribute to this persistence. Of these, 48 TA modules belong to the vapBC (virulence associated protein) gene family. VapC toxins are PIN domain endonucleases that, in Enterobacteria,
Tollervey, David, Winther, Kristoffer Skovbo, Tree, Jai, Gerdes, Kenn   +3 more
openaire   +1 more source

Genetic features of bla_NDM-1 harboring Klebsiella pneumoniae isolates from Kerman, Iran. [PDF]

BMC Microbiol
Aslani S, Afgar A, Ekrami A, Savari M, Isaei E, Hosseini SM, Kalantar-Neyestanaki D.   +6 more
europepmc   +1 more source

The Prevalence and Diversity of Marine Toxin-Antitoxin Systems. [PDF]

Mar Drugs
Liu C, Guo Y, Gu J, Wei Z, Chen P, Wang X.   +5 more
europepmc   +1 more source

Structural and functional characterization of VapBC52 toxin-antitoxin system from Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Singh M, Singh C, Nair AV, Ahmad I, Sharma A, Bhasin M, Jain V, Singh R, Thakur KG.   +8 more
europepmc   +1 more source

Editorial for Special Issue "Molecular Research in Vaccinology and Vaccine Development". [PDF]

Curr Issues Mol Biol
Farsang A.
europepmc   +1 more source

Protein-Protein Interactions as Promising Molecular Targets for Novel Antimicrobials Aimed at Gram-Negative Bacteria. [PDF]

Int J Mol Sci
Maj P, Trylska J.
europepmc   +1 more source

Genomic and functional characterization of a <i>bla</i>_NDM-1 and <i>tmexCD2-toprJ2</i> co-producing <i>Klebsiella quasipneumoniae</i> (KL159/ST1929) reveals plasmid-mediated suppression of virulence. [PDF]

Microbiol Spectr
Nie F, Zou T, Luo R, Liu M, Lai H, Xiao Y, Zhang J, Liu Y, Zhang W, Li P, Xiang T.   +10 more
europepmc   +1 more source

tRNA^fMet Inactivating Mycobacterium tuberculosis VapBC Toxin-Antitoxin Systems as Therapeutic Targets. [PDF]

Antimicrob Agents Chemother, 2022
Chauhan U, Barth VC, Woychik NA.
europepmc   +1 more source