Results 91 to 100 of about 1,147 (168)
Mechanism of RNA cleavage by VapC from Pyrobaculum aerophilum [PDF]
, 2012 Proteins belonging to the PIN-domain family are widespread across bacteria, archaea and eukaryotes. PIN-domain structures are well characterised and contain three highly conserved acidic residues that are orientated to form the active site of the enzyme.
Duyvestyn, Johanna Maria
core
The Biology and Biochemistry of PhoH2 proteins [PDF]
, 2013 PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core
The Biochemistry of VapBC Toxin-Antitoxins [PDF]
, 2011 The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey ...
McKenzie, Joanna Leigh
core
Model for the regulation of the vapBC-1 locus.
, 2013 (A) During colonization under favourable conditions, the VapBC-1 complex binds to and autorepresses TA operon transcription. (B) Stress induces Lon and Clp proteases that degrade VapB-1, releasing active VapC-1 toxin.
Sehresh Saleem (329519) +2 more
core +1 more source
, 1999 Single-unit recordings were made from the basal-ganglia- and cerebellar-receiving areas of the thalamus in two monkeys trained to make arm movements that were either visually triggered (VT) or internally generated (IG).
J. F. Stein +7 more
core +1 more source
Competition binding of 50TIR and 50US by Vap proteins.
, 2013 Gel shift products from addition of 50US substrate into samples containing 50TIR substrate and either (A) VapBC-1 or (B) VapC-1 at a 150∶1 molar ratio of VapC-1 protein to DNA. VapB-1 and VapC-1 are at a 3∶1 molar ratio in the VapBC-1 samples, but VapC-1∶
Sehresh Saleem (329519) +2 more
core +1 more source
, 2009 A leptospirose é uma zoonose mundial causada por bactéria do gênero Leptospira. O desenvolvimento de uma vacina de subunidade eficaz seria de grande interesse em saúde pública.
Luana Melo Lopes, Lopes, Luana Melo
core +1 more source
, 2014 Although PIN (PilT N-terminal)-domain proteins are known to have ribonuclease activity, their specific mechanism of action remains unknown. VapCs form a family of ribonucleases that possess a PIN-domain assembly and are known as toxins. The activities of
Matthias, Wilmanns +8 more
core +1 more source
, 2016 The major human pathogen Mycobacterium tuberculosis can survive in the host organism for decades without causing symptoms. A large cohort of Toxin-Antitoxin (TA) modules contribute to this persistence. Of these, 48 TA modules belong to the vapBC (virulence associated protein) gene family. VapC toxins are PIN domain endonucleases that, in Enterobacteria,
Tollervey, David +3 more
openaire +1 more source
Os sistemas Toxina-Antitoxina (TA) são um dos mecanismos de adaptação bacteriana a condições adversas. A bactéria L. interrogans sorovar Copenhageni estirpe Fiocruz L1-130 contém nove sistemas TA putativos, destes, foram caracterizados experimentalmente ...
Azevedo, Bruna Oliveira Pigatto
core +1 more source